Jindal Neerja, Arora Usha, Singh Kamaldeep
Microbiology Department, Government Medical College, Amritsar, India.
Jpn J Infect Dis. 2008 Jan;61(1):79-81.
Three groups of populations at high risk of human immunodeficiency virus (HIV) infection, i.e., injecting drug users (IDUs), truckers, and attendees of sexually transmitted disease (STD) clinic of Amritsar (Punjab), Northern India, were studied in order to determine the prevalence of HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) infections. Of the 157 IDUs, 16.6, 17.8, and 33.7% were found to be positive for HIV, HBV, and HCV infections, respectively. HCV showed significant difference (P<0.01) and very high rate (8.3%) of co-infection with HIV. In truckers, maximum seropositivity was associated with HIV (19%), i.e., significantly higher than that of HBV (6%, P<0.01) and HCV (3%, P<0.01). In STD clinic attendees, the highest rate of seroprevalence was that of HIV (4.3%), followed closely by that of HBV (3.7%), and HCV (2.6%). The present study emphasizes the need for early screening for HBV and HCV infections of all those also at high risk for HIV infection, and the results highlight the importance of relevant targeted interventions in these populations.
为了确定人类免疫缺陷病毒（HIV）、乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）感染的流行情况，对三组感染HIV风险较高的人群进行了研究，即印度北部旁遮普邦阿姆利则市的注射吸毒者（IDU）、卡车司机以及性传播疾病（STD）诊所的就诊者。在157名注射吸毒者中，分别有16.6%、17.8%和33.7%的人被检测出HIV、HBV和HCV感染呈阳性。HCV与HIV的合并感染率差异显著（P<0.01），且合并感染率很高（8.3%）。在卡车司机中，血清阳性率最高的是HIV（19%），即显著高于HBV（6%，P<0.01）和HCV（3%，P<0.01）。在STD诊所就诊者中，血清流行率最高的是HIV（4.3%），其次是HBV（3.7%）和HCV（2.6%）。本研究强调了对所有HIV感染高风险人群进行HBV和HCV感染早期筛查的必要性，研究结果突出了在这些人群中进行相关针对性干预措施的重要性。
