Department of Virology, Niigata Prefectural Institute of Public Health and Environmental Sciences, Niigata 950-2144, Japan.
Jpn J Infect Dis. 2010 Nov;63(6):405-11.
A molecular epidemiological study of rotavirus (RV) and norovirus (NoV) infections was carried out in Nha Trang city in Vietnam between December 2005 and June 2006. RV and NoV were detected in 87 (47.5%) and 12 (6.6%) of the 183 fecal specimens from children hospitalized with acute gastroenteritis, respectively. The majority of patients with RV and NoV were children younger than 2 years of age. The most frequent RV genotypes detected were G3 (n=37, 42.5%) and G1 (n=28, 32.2%) for G type, P[8] (n=61, 70.1%) for P type, and G3P[8] (n=33, 38.0%) and G1P[8] (n=18, 20.7%) for the G and P genotype combination. GII.12 was the most common genotype (6/12, 50%) for NoV, followed by GII.4 (4/12, 33.3%), and we also identified a rare type (GII.19). The results of this study highlight the increased incidence of G3P[8] and the presence of many OP354-like P[8] RVs, as well as the GII.4 2003 Asia variant of NoVs. Furthermore, the first case of GII.19 of NoV in Vietnam is reported.
2005 年 12 月至 2006 年 6 月，在越南芽庄市进行了轮状病毒（RV）和诺如病毒（NoV）感染的分子流行病学研究。在因急性胃肠炎住院的 183 份粪便样本中，分别检测到 87 份（47.5%）和 12 份（6.6%）RV 和 NoV 感染。RV 和 NoV 感染的大多数患者为 2 岁以下儿童。检测到的最常见 RV 基因型为 G3（n=37，42.5%）和 G1（n=28，32.2%），G 型；P[8]（n=61，70.1%），P 型；G3P[8]（n=33，38.0%）和 G1P[8]（n=18，20.7%），G 和 P 基因型组合。NoV 最常见的基因型是 GII.12（6/12，50%），其次是 GII.4（4/12，33.3%），我们还鉴定出一种罕见的基因型（GII.19）。本研究结果表明，G3P[8]的发病率增加，存在许多 OP354 样 P[8]RV 以及 NoV 的 GII.4 2003 年亚洲变异株。此外，报道了越南首例 GII.19 型 NoV 病例。
