University of Missouri-Kansas City School of Pharmacy, USA.
J Cardiovasc Nurs. 2011 Jul-Aug;26(4):E12-9. doi: 10.1097/JCN.0b013e3181efea94.
Adherence to evidence-based therapies has emerged as one of the great challenges of translating discoveries to clinical care to optimize patient outcomes. In particular, nonadherence to lifesaving medications continues to trouble health care systems. We conducted a series of studies to investigate why cardiac patients stop life-sustaining medications and to develop a tool to proactively address medication adherence issues. We could find no available preventive tools for communicating with patients about their medications in the clinical setting. In this article, we summarize the process of developing such a tool.
We used a mixed-methods approach in a series of studies that included examining quantitative data from a large patient registry, conducting in-depth qualitative patient interviews, creating items representative of the qualitative findings, pilot testing items with heart patients, surveying an expert panel to establish content validity, and conducting in-depth interviews with health care providers to assess implementation opportunities.
Patient interviews revealed that patients' values and beliefs, barriers to treatment, and prior medication-taking behavior were of primary importance in understanding medication discontinuance. Pilot testing, expert panel review, and an implementation feasibility evaluation resulted in an 11-item communication guide to be used in a variety of health care settings. Clinicians need an efficient way of systematically communicating with patients about heart medications to identify barriers and to initiate preventive interventions when patients report barriers or challenges to medication adherence.
将循证疗法应用于临床实践以优化患者结局,这一过程中面临的最大挑战之一是患者对疗法的遵从性。特别是,患者不遵从救命药物的使用,这一问题一直困扰着医疗体系。我们开展了一系列研究,旨在调查患者停止使用维持生命的药物的原因,并开发一种主动解决药物遵从性问题的工具。我们在临床环境中没有找到可用于与患者就其药物治疗进行沟通的现有预防工具。在本文中,我们总结了开发此类工具的过程。
我们采用混合方法,在一系列研究中,我们利用了大型患者登记处的定量数据,对患者进行深入的定性访谈,生成与定性研究结果具有代表性的项目,在心脏病患者中对项目进行试点测试,对专家小组进行调查以确定内容效度,并对医疗保健提供者进行深入访谈以评估实施机会。
患者访谈揭示了患者的价值观和信念、治疗障碍以及既往用药行为是理解停药的主要因素。试点测试、专家小组审查和实施可行性评估得出了一个 11 项的沟通指南,可用于各种医疗保健环境。临床医生需要一种有效的方法来系统地与患者就心脏药物治疗进行沟通,以识别障碍,并在患者报告药物遵从性障碍或挑战时启动预防干预措施。