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灰色链霉菌甘油操纵子推定调控基因及主要启动子区域的核苷酸序列。

Nucleotide sequence of the putative regulatory gene and major promoter region of the Streptomyces griseus glycerol operon.

作者信息

Bolotin A, Biro S

机构信息

Institute of Genetics and Selection of Industrial Microorganisms, Moscow, U.S.S.R.

出版信息

Gene. 1990 Mar 1;87(1):151-2. doi: 10.1016/0378-1119(90)90508-o.

DOI:10.1016/0378-1119(90)90508-o
PMID:2110096
Abstract

Nucleotide sequencing of the deduced major promoter region of the glycerol utilization operon and an upstream regulatory gene of Streptomyces griseus reveals extensive similarity to the previously sequenced homologous S. coelicolor region [Smith and Chater, J. Mol. Biol. 204 (1988) 569-580]. However, regions showing extensive divergence are found in the noncoding parts of the sequence. These may help to evaluate the significance of various sequence features in relation to promoter activity.

摘要

对灰色链霉菌甘油利用操纵子推导的主要启动子区域和一个上游调控基因进行核苷酸测序,结果显示与之前测序的天蓝色链霉菌同源区域[史密斯和查特,《分子生物学杂志》204 (1988) 569 - 580]有广泛的相似性。然而,在序列的非编码部分发现了存在广泛差异的区域。这些区域可能有助于评估各种序列特征与启动子活性之间的关系。

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