Fortunak Joseph, Confalone Pat N, Grosso John A
Curr Opin Drug Discov Devel. 2010;13(6):642-4.
Microreactor technology holds great promise for simplifying process chemistry. The design of microreactors inherently simplifies heat transfer and flow. Continuous processing on a commercial scale is also achievable using these reactors, providing significant improvements in efficiency compared with batch processing. Two-phase reactions with liquid-gas and liquid-solid phases present difficulties for microreactor-based processing; however, advances in reactor design are providing some solutions to such challenges. The potential efficiencies provided by microreactors suggest that this technology will be adopted increasingly for widespread commercial applications, particularly following greater investment by companies and further improvements in engineering.
微反应器技术在简化过程化学方面具有巨大潜力。微反应器的设计本质上简化了传热和流动。使用这些反应器还可以实现商业规模的连续加工,与间歇加工相比,效率有显著提高。液-气和液-固两相反应给基于微反应器的加工带来了困难;然而,反应器设计的进步正在为这些挑战提供一些解决方案。微反应器提供的潜在效率表明,这项技术将越来越多地被广泛应用于商业领域,特别是在企业加大投资和工程进一步改进之后。