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嗜酸乳杆菌对白色念珠菌的抑制作用:过氧化物酶系统参与的证据。

Inhibition of Candida albicans by Lactobacillus acidophilus: evidence for the involvement of a peroxidase system.

作者信息

Fitzsimmons N, Berry D R

机构信息

Microbiology Laboratory, Crosshouse Hospital, Kilmarnock, Scotland.

出版信息

Microbios. 1994;80(323):125-33.

PMID:7898374
Abstract

A range of cultures of Lactobacillus acidophilus was isolated from patients using oral, vaginal and endocervical swabs. These were investigated for their ability to (1) inhibit the growth of Candida albicans, and (2) generate peroxidase, hydrogen peroxide and hypothiocyanite. Inhibition of Candida albicans and hydrogen peroxide production was detected in nine out of twelve strains whereas peroxidase production was only detected in three out of twelve strains, all from oral swabs. Hypothiocyanite production was detected in two strains and it was only detected in these strains after growth in MRS medium in aerobic conditions.

摘要

使用口腔、阴道和宫颈拭子从患者中分离出一系列嗜酸乳杆菌培养物。对这些培养物进行了如下研究:(1)抑制白色念珠菌生长的能力,以及(2)产生过氧化物酶、过氧化氢和次硫氰酸盐的能力。在12株菌株中,有9株检测到对白色念珠菌的抑制作用和过氧化氢的产生,而过氧化物酶的产生仅在12株菌株中的3株中检测到,且这3株均来自口腔拭子。在2株菌株中检测到次硫氰酸盐的产生,并且仅在有氧条件下于MRS培养基中生长后的这些菌株中检测到。

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Microbios. 1994;80(323):125-33.
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