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肯尼亚患肠胃炎儿童的野生型重组人星状病毒株的证据。

Evidence of a recombinant wild-type human astrovirus strain from a Kenyan child with gastroenteritis.

机构信息

Department of Medical Virology, Faculty of Health Sciences, University of Pretoria/National Health Laboratory Service, P.O. Box 2034, Pretoria 0001, South Africa.

出版信息

J Clin Microbiol. 2011 Feb;49(2):728-31. doi: 10.1128/JCM.01093-10. Epub 2010 Nov 24.

Abstract

A human astrovirus (HAstV) strain from Kenya was characterized by nucleotide sequence analysis. Sequences from open reading frame 1a (ORF1a) clustered with genotype 6/7, those from ORF1b clustered with genotype 3, and those from ORF2 clustered with genotype 2. A recombination point in the ORF1b-ORF2 junction was identified, with a second possible recombination point within the ORF1a region.

摘要

对肯尼亚分离的一株人星状病毒(HAstV)进行了核苷酸序列分析。ORF1a 的序列与基因型 6/7 聚为一簇,ORF1b 的序列与基因型 3 聚为一簇,ORF2 的序列与基因型 2 聚为一簇。在 ORF1b-ORF2 交界处鉴定到一个重组点,在 ORF1a 区域内还存在另一个可能的重组点。

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