Naevdal Erlend Fjell, Nylund Kim, Gilja Odd Helge
Institutt for indremedisin, Universitetet i Bergen, 5021 Bergen, Norway.
Tidsskr Nor Laegeforen. 2010 Nov 18;130(22):2230-4. doi: 10.4045/tidsskr.09.0205.
During the last 15 years transabdominal ultrasonography has been used increasingly for assessment of patients with inflammatory bowel disease. Approximately 300 such examinations are performed annually in the medical department at Haukeland University Hospital. This article reviews the use of ultrasonography in ulcerative colitis and Crohn's disease.
The articles referred to were found in our own literature archive or in PubMed (a non-systematic search was performed).
Patients with Crohn's disease often have thickened bowel wall and altered wall structure (as shown by transabdominal ultrasonography). In ulcerative colitis the wall structure is often preserved, the disease limited to the colon and the wall only slightly to moderately thickened. The sensitivity for diagnosing inflammatory bowel disease is around 85 % and the specificity 95 % and that for Crohn's disease is 88 % and 93 %. In patients with complicated Crohn's disease transabdominal ultrasonography is best for detecting stenoses (sensitivity 74-100 %, specificity 91-100 %), but less effective for fistulas (sensitivity 71 %, specificity 96 %) and abscesses (sensitivity 81 %, specificity 93 %). Local hyperaemia in the bowel wall suggests inflammation and can be detected with colour Doppler.
Transabdominal ultrasonography is useful for primary diagnostics and in follow-up of patients with inflammatory bowel disease. The examinations are most successful when performed by a clinician who knows the patient and is familiar with bowel ultrasonography.
在过去15年中,经腹超声检查越来越多地用于评估炎症性肠病患者。豪克兰德大学医院内科每年大约进行300次此类检查。本文综述了超声检查在溃疡性结肠炎和克罗恩病中的应用。
所引用的文章来自我们自己的文献存档或PubMed(进行了非系统性检索)。
克罗恩病患者的肠壁通常增厚且壁结构改变(经腹超声检查显示)。在溃疡性结肠炎中,壁结构通常保留,疾病局限于结肠,壁仅轻度至中度增厚。诊断炎症性肠病的敏感性约为85%,特异性为95%;诊断克罗恩病的敏感性为88%,特异性为93%。在患有复杂性克罗恩病的患者中,经腹超声检查最适合检测狭窄(敏感性74 - 100%,特异性91 - 100%),但对瘘管(敏感性71%,特异性96%)和脓肿(敏感性81%,特异性93%)的检测效果较差。肠壁局部充血提示炎症,可通过彩色多普勒检测到。
经腹超声检查对炎症性肠病患者的初步诊断和随访有用。当由了解患者且熟悉肠道超声检查的临床医生进行检查时,最为成功。