Caudle Abigail S, Ross Merrick I
Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 444, Houston, TX 77030, USA.
Surg Oncol Clin N Am. 2011 Jan;20(1):133-44. doi: 10.1016/j.soc.2010.09.010.
Although the conventional paradigm for treating metastatic melanoma relies on systemic therapies, a surgical approach should be strongly considered in selected patients. A surgical approach may not be appropriate for all patients, but it can offer a rapid clearance of disease without the toxicity of systemic therapy. Patient selection is of paramount importance for surgery to be effective. The rationale for surgical intervention in the management of metastatic melanoma, selection factors to be considered, published results, and future directions are discussed in this article.
尽管治疗转移性黑色素瘤的传统模式依赖于全身治疗，但对于特定患者应强烈考虑手术方法。手术方法可能并不适用于所有患者，但它可以在不产生全身治疗毒性的情况下迅速清除病灶。患者选择对于手术取得成效至关重要。本文讨论了转移性黑色素瘤管理中手术干预的基本原理、需考虑的选择因素、已发表的结果以及未来方向。
