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有氧运动与联合运动疗法治疗纤维肌痛综合征女性患者的随机对照试验。

Aerobic exercise versus combined exercise therapy in women with fibromyalgia syndrome: a randomized controlled trial.

机构信息

Physical Education and Sport Department, University of Seville, Spain.

出版信息

Arch Phys Med Rehabil. 2010 Dec;91(12):1838-43. doi: 10.1016/j.apmr.2010.09.006.

DOI:10.1016/j.apmr.2010.09.006
PMID:21112423
Abstract

OBJECTIVE

To investigate the effects of supervised aerobic exercise (AE) and a combined program of supervised aerobic, muscle strengthening, and flexibility exercises (combined exercise [CE]) on important health outcomes in women with fibromyalgia syndrome (FMS).

DESIGN

Randomized controlled trial.

SETTING

Community-based supervised intervention.

PARTICIPANTS

Women (N=64) with a diagnosis of FMS according to the American College of Rheumatology criteria.

INTERVENTION

Participants were randomly allocated to 1 of 3 groups: supervised AE, supervised CE, or usual-care control. Exercise sessions were performed twice weekly (45-60min/session) for 24 weeks.

MAIN OUTCOME MEASURES

The primary outcome measure was the Fibromyalgia Impact Questionnaire (FIQ). Exploratory outcome measures were the 36-Item Short-Form Health Survey, Beck Depression Inventory (BDI), aerobic capacity (6-minute walk test), hand-grip strength, and range of motion in the shoulders and hips.

RESULTS

Compliance with both interventions was excellent, with women in the exercise groups attending more than 85% of sessions. A 14% to 15% improvement from baseline in total FIQ score was observed in the exercise groups (P≤.02) and was accompanied by decreases in BDI scores of 8.5 (P<.001) and 6.4 (P<.001) points in the AE and CE groups, respectively. Relative to nonexercising controls, CE evoked improvements in the SF-36 Physical Functioning (P=.003) and Bodily Pain (P=.003) domains and was more effective than AE for evoking improvements in the Vitality (P=.002) and Mental Health (P=.04) domains. Greater improvements also were observed in shoulder/hip range of motion and handgrip strength in the CE group.

CONCLUSION

Given the equivalent time commitment required for AE and CE, our results suggest that women with FMS can gain additional health benefits by engaging in a similar volume of CE.

摘要

目的

研究监督下的有氧运动(AE)和监督下的有氧运动、肌肉强化和柔韧性运动相结合的方案(综合运动[CE])对纤维肌痛综合征(FMS)女性重要健康结果的影响。

设计

随机对照试验。

设置

基于社区的监督干预。

参与者

根据美国风湿病学院标准诊断为 FMS 的女性(N=64)。

干预

参与者被随机分配到 3 个组之一:监督 AE、监督 CE 或常规护理对照。运动课程每周进行 2 次(每次 45-60 分钟),持续 24 周。

主要观察指标

主要观察指标是纤维肌痛影响问卷(FIQ)。探索性观察指标是 36 项简短健康调查问卷(SF-36)、贝克抑郁量表(BDI)、有氧能力(6 分钟步行测试)、手握力和肩部及臀部活动范围。

结果

两种干预措施的依从性都非常好,运动组的女性参加了超过 85%的课程。运动组的总 FIQ 评分从基线提高了 14%至 15%(P≤.02),同时 AE 和 CE 组的 BDI 评分分别降低了 8.5(P<.001)和 6.4 分(P<.001)。与不运动的对照组相比,CE 组在 SF-36 身体机能(P=.003)和躯体疼痛(P=.003)领域的改善更为显著,并且在活力(P=.002)和心理健康(P=.04)领域的改善效果优于 AE 组。CE 组的肩部/臀部活动范围和手握力也有更大的改善。

结论

鉴于 AE 和 CE 需要的时间投入相当,我们的结果表明,患有 FMS 的女性可以通过进行类似量的 CE 获得额外的健康益处。

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