Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Vasc Med. 2011 Apr;16(2):119-30. doi: 10.1177/1358863X10388346. Epub 2010 Nov 26.
Thromboembolic complications are the second leading cause of death in cancer patients. In contrast to the large body of literature on venous thromboembolism (VTE), relatively few reports have focused on the pathogenesis, incidence, management and outcomes of arterial thromboembolic events in patients with malignancy. The purpose of this article is to review the current literature on the etiology, mechanisms, and prognosis of arterial thromboembolic events in cancer patients and outline appropriate screening and management guidelines that may help lower the rates of morbidity and mortality related to these events.
血栓栓塞并发症是癌症患者死亡的第二大主要原因。与大量关于静脉血栓栓塞症 (VTE) 的文献相比,关于恶性肿瘤患者动脉血栓栓塞事件的发病机制、发生率、治疗和结局的报道相对较少。本文的目的是回顾目前关于癌症患者动脉血栓栓塞事件的病因、机制和预后的文献,并概述适当的筛查和管理指南,这些指南可能有助于降低与这些事件相关的发病率和死亡率。