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一名肝硬化患者因膀胱鳞状细胞癌并发Trousseau综合征伴门静脉血栓形成。

Portal Vein Thrombosis Associated with Trousseau Syndrome due to Urinary Bladder Squamous Cell Carcinoma in a Liver Cirrhosis Patient.

作者信息

Kimura Naruhiro, Tsuchiya Atsunori, Oda Chiyumi, Kimura Atsushi, Hosaka Kazunori, Tominaga Kentaro, Hayashi Kazunao, Abé Tatsuya, Umezu Hajime, Terai Shuji

机构信息

Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Japan.

Division of Molecular and Diagnostic Pathology, Niigata University Graduate School of Medical and Dental Sciences, Japan.

出版信息

Intern Med. 2020 Aug 15;59(16):1971-1975. doi: 10.2169/internalmedicine.4112-19. Epub 2020 May 23.

Abstract

A 75-year-old woman with liver cirrhosis was admitted for treatment of portal vein thrombosis (PVT). Computed tomography (CT) showed PVT, massive ascites, and multiple abdominal organ embolism. Blood tests revealed a decreased liver function (Child-Pugh grade C). Language impairment followed by progressive left hemi-paralysis was subsequently detected. Magnetic resonance imaging revealed multiple small acute cerebral infarctions and, on CT, a 30-mm bladder tumour; a biopsy specimen examination showed squamous cell carcinoma. Her general condition worsened rapidly, and the best supportive care was chosen. Our findings suggest that, in patients with PVT, Trousseau syndrome should be considered, even in cases of liver cirrhosis.

摘要

一名75岁的肝硬化女性因门静脉血栓形成(PVT)入院治疗。计算机断层扫描(CT)显示有PVT、大量腹水和多处腹部器官栓塞。血液检查显示肝功能下降(Child-Pugh C级)。随后检测到语言障碍,接着出现进行性左侧偏瘫。磁共振成像显示多处小的急性脑梗死,CT显示有一个30毫米的膀胱肿瘤;活检标本检查显示为鳞状细胞癌。她的总体状况迅速恶化,于是选择了最佳支持治疗。我们的研究结果表明,对于PVT患者,即使是肝硬化患者,也应考虑存在特鲁索综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56cb/7492126/6ecc767ea2a4/1349-7235-59-1971-g001.jpg

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