Barbosa-Martins João, Costa Ana, Costa Magda, Formigo Mariana, Cotter Jorge
Medical Oncology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Internal Medicine Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Eur J Case Rep Intern Med. 2022 Jul 4;9(7):003386. doi: 10.12890/2022_003386. eCollection 2022.
Arterial thrombosis and Budd-Chiari syndrome are rare conditions in lung cancer patients. We report the case of a 53-year-old woman who presented with respiratory symptoms, lumbar pain, weight and appetite loss, and an x-ray showing a lung nodule and diffuse micro-opacities. She was diagnosed with lung neoplasia with extensive lung, liver, lymph node and bone metastases. After discharge she was readmitted with a respiratory infection, and as her condition deteriorated, computed tomography was performed and revealed ischaemic areas in the spleen and kidney, and venous thrombosis, related to Budd-Chiari syndrome, with hepatic ischaemia. Despite hypocoagulation, her clinical condition deteriorated and she died soon afterwards.
Acute ischaemic arterial events are rare in cancer patients.Budd-Chiari syndrome associated with lung cancer is rare.Both presentations have a poor prognosis, so early diagnosis and intervention are imperative.
动脉血栓形成和布加综合征在肺癌患者中是罕见病症。我们报告一例53岁女性病例，该患者出现呼吸道症状、腰痛、体重减轻和食欲减退，X线显示肺部有结节及弥漫性微阴影。她被诊断为患有肺肿瘤，伴有广泛的肺、肝、淋巴结和骨转移。出院后，她因呼吸道感染再次入院，随着病情恶化，进行了计算机断层扫描，结果显示脾脏和肾脏有缺血区域，以及与布加综合征相关的静脉血栓形成和肝缺血。尽管存在低凝状态，但她的临床状况仍恶化，不久后死亡。
急性缺血性动脉事件在癌症患者中罕见。与肺癌相关的布加综合征罕见。这两种情况预后均较差，因此早期诊断和干预至关重要。
