Influence of combined aerobic and resistance training on metabolic control, cardiovascular fitness and quality of life in adolescents with type 1 diabetes: a randomized controlled trial.

OBJECTIVE

To evaluate the effect of combined exercise training on metabolic control, physical fitness and quality of life in adolescents with type 1 diabetes.

DESIGN

A double-blind randomized controlled trial with patients receiving combined aerobic and strength or no training.

SETTING

University Hospital Ghent (Belgium).

SUBJECTS

Sixteen children with type 1 diabetes were randomized into a control group (n = 8) and an intervention group (n = 8).

INTERVENTIONS

Patients participated twice a week for 20 weeks in the combined aerobic and strength group. The control group continued their normal daily activities.

MAIN MEASURES

Before and after the intervention anthropometric variables (weight, length, BMI, body composition), metabolic control (glycaemia, HbA1c, daily insulin injected), aerobic capacity (peak Vo(2), peak power, peak heart rate, 6-minute walk distance), strength (1 repetition maximum of upper and lower limb, hand grip strength, muscle fatigue resistance, sit-to-stand) and quality of life (SF-36) were assessed.

RESULTS

At baseline, none of the measured parameters differed significantly between the two groups. There was no significant evolution in the groups concerning anthropometric indices, glycaemia and HbA1c. However, the daily doses of insulin injected were significantly lowered in the training group (0.96 IU/kg.day pre versus 0.90 IU/kg.day post; P < 0,05), while it was increased in the control group. Physical fitness increased significantly in the training group. General health, vitality and role emotional had a tendency to improve.

CONCLUSION

Combined exercise training seemed to lower daily insulin requirement and improve physical fitness, together with better well-being.