Gray R J, Sloan P, Quayle A A, Carter D H
Department of Oral and Maxillo-Facial Surgery, Turner Dental School, University Dental Hospital of Manchester, England.
Int J Oral Maxillofac Surg. 1990 Apr;19(2):65-71. doi: 10.1016/s0901-5027(05)80196-1.
This investigation was undertaken to correlate the scintigraphic and histological features of condylar hyperplasia to identify consistent diagnostic findings. A series of 34 surgically excised condyles were examined from a 5 year period. Of these, 20 were diagnosed clinically and histologically as condylar hyperplasia. In 18 of these the presentation was one of increasing facial asymmetry. In all 20 cases there was an increased uptake of Technetium 99 as determined by gamma scintigraphy. The thickness of the fibrous articular layer, undifferentiated germinal mesenchyme layer and the hyperplastic cartilage layer were measured using an eyepiece graticule and the presence and frequency of islands of cartilage in the subchondral bone were noted. 7 patients received tetracycline hydrochloride 14 and 4 days pre-operatively in an attempt to quantify the calcification rate. An uninterrupted layer of undifferentiated germinal mesenchyme is a consistent feature of condylar hyperplasia. An increased uptake on scintigraphy is proportionally related to the thickness of the hypertrophic cartilage and not only to the presence but also the frequency of cartilage islands in the subchondral bone.
本研究旨在关联髁突增生的闪烁扫描特征和组织学特征，以确定一致的诊断结果。在5年期间对一系列34个手术切除的髁突进行了检查。其中，20个在临床和组织学上被诊断为髁突增生。其中18例表现为面部不对称加重。在所有20例病例中，通过γ闪烁扫描确定锝99摄取增加。使用目镜测微尺测量纤维关节层、未分化生发间充质层和增生软骨层的厚度，并记录软骨下骨中软骨岛的存在情况和频率。7例患者在术前14天和4天接受盐酸四环素治疗，试图量化钙化率。未分化生发间充质的不间断层是髁突增生的一致特征。闪烁扫描上摄取增加与肥厚软骨的厚度成比例相关，不仅与软骨下骨中软骨岛的存在有关，还与软骨岛的频率有关。
