Karyotyping，在易性癖中是否有价值？
Karyotyping, is it worthwhile in transsexualism?
机构信息
Department of Endocrinology-Andrology, Center for Sexology and Genderproblems, Ghent University Hospital, Ghent, Belgium.
出版信息
J Sex Med. 2011 Feb;8(2):475-8. doi: 10.1111/j.1743-6109.2010.02130.x. Epub 2010 Nov 29.
INTRODUCTION
Karyotyping is often performed in transsexual individuals.
AIM
Quantification and characterization of karyotype findings and abnormalities in transsexual persons.
MAIN OUTCOME MEASURES
Karyotypes were listed both in male-to-female and in female-to-male transsexual persons.
METHODS
The data were collected through a retrospective study.
RESULTS
Karyotypes of 368 transsexual individuals (251 male-to-female, 117 female-to-male) are described. Normal findings were found in 97.55%. Prevalence of abnormal karyotypes was 3.19% among male-to-female, and 0.85% among female-to-male transsexuals. Nine karyotypes showed variations; Klinefelter syndrome was confirmed in three persons, whereas others displayed autosomal aberrations.
CONCLUSION
Karyotyping is only of very limited information in the transsexual population.
简介
染色体核型分析常用于易性症患者。
目的
对易性症患者的核型结果和异常进行量化和特征描述。
主要观察指标
列出男转女和女转男易性症患者的核型。
方法
通过回顾性研究收集数据。
结果
描述了 368 名易性症患者（251 名男转女，117 名女转男）的核型。正常核型占 97.55%。男转女易性症患者中异常核型的发生率为 3.19%，女转男易性症患者中为 0.85%。9 种核型显示出变异；3 名患者被确诊为克氏综合征，而其他人则表现出常染色体异常。
结论
染色体核型分析在易性症人群中仅提供非常有限的信息。
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