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腹腔镜处理绝经后妇女卵巢性索-间质早期肿瘤:一种建议的方法。

Laparoscopical management ovarian early sex cord-stromal tumors in postmenopausal women: a proposal method.

机构信息

Division of Experimental Endoscopic Surgery, Imaging, Minimally Invasive Therapy and Technology, Department of Obstetrics and Gynaecology, Vito Fazzi Hospital, P.zza Muratore, 73100, Lecce, Italy.

出版信息

Arch Gynecol Obstet. 2011 Mar;283 Suppl 1:87-91. doi: 10.1007/s00404-010-1773-x. Epub 2010 Nov 30.

Abstract

BACKGROUND

Ovarian sex-cord stromal tumor (SCST) comprises 5% of the ovarian neoplasm; it occurs as an ovarian mass or hemoperitoneum, and the surgical management of SCST is not well defined at early stage and in adult patients.

PURPOSE OF THE STUDY

The authors tested to test the total not radical laparoscopic management of SCST in postmenopausal women at early stage.

METHODS

Three postmenopausal women were admitted in University-affiliated hospitals for pelvic pain, ovarian complex mass and genital bleeding. Preoperative clinical and instrumental examination suspected an ovarian tumor; therefore, a total laparoscopic approach was attempted. All patients underwent laparoscopic oophorectomy with the frozen section, who suggested for ovarian SCST; one woman received a total laparoscopic hysterectomy plus other oophorectomy, two received only the complementary oophorectomy, all without intensive surgical staging by with pelvic and para-aortic lymphadenectomy, appendectomy, peritoneal biopsies, and omentectomy.

RESULTS

All patients completed surgery without intrasurgical and postsurgical complications, with a fast dismissal. They are, currently, in long-term follow-up, with a 100% of survival after 3 years and with none morbility and morbidity.

CONCLUSIONS

In order to fast restore and preserve women's integrity, total laparoscopic approach of early SCST in adult age, without intensive radical staging, could be an appropriate clinical choice, since these tumors at slow growth, recurring locally and only a long time after initial treatment. This minimally invasive management could be suggested in association with a long-term follow-up, as possible "wait and see" postoperative option.

摘要

背景

卵巢性索间质肿瘤(SCST)占卵巢肿瘤的 5%;它以卵巢肿块或血性腹水为表现,且早期和成年患者的 SCST 手术管理尚未明确。

研究目的

作者旨在测试早期绝经后妇女的 SCST 进行非根治性腹腔镜治疗。

方法

3 名绝经后妇女因盆腔疼痛、卵巢复杂肿块和生殖器出血而入住大学附属医院。术前临床和仪器检查怀疑为卵巢肿瘤;因此,尝试了完全腹腔镜方法。所有患者均接受腹腔镜卵巢切除术和冷冻切片检查,结果提示为卵巢 SCST;1 名妇女接受了全腹腔镜子宫切除术加另一次卵巢切除术,2 名妇女仅接受了补充性卵巢切除术,均未进行包括盆腔和主动脉旁淋巴结切除术、阑尾切除术、腹膜活检和网膜切除术在内的强化外科分期。

结果

所有患者均顺利完成手术,无术中及术后并发症,且快速出院。目前,她们正在进行长期随访,3 年后的生存率为 100%,且无任何并发症和发病率。

结论

为了快速恢复和保留女性的完整性,对于成年早期的 SCST,不进行强化根治性分期的完全腹腔镜方法可能是一种合适的临床选择,因为这些肿瘤生长缓慢,仅在初始治疗后很长时间才会局部复发。这种微创管理可以与长期随访相结合,作为一种可能的“观望”术后选择。

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