Hackley Vincent A, Clogston Jeffrey D
Ceramics Division, National Institute of Standards and Technology, Gaithersburg, MD, USA.
Methods Mol Biol. 2011;697:35-52. doi: 10.1007/978-1-60327-198-1_4.
Particle size characterization is of particular importance to nanomedicine. The size similarity of nanoparticles to biological moieties is believed to impart many of their unique medical properties. Here we present a method for sample preparation and the determination of mean nanoparticle size (hydrodynamic diameter) using batch-mode dynamic light scattering (DLS) in dilute aqueous suspensions. We then demonstrate this method for 30 nm colloidal gold.
颗粒尺寸表征对于纳米医学尤为重要。据信，纳米颗粒与生物部分的尺寸相似性赋予了它们许多独特的医学特性。在此，我们介绍一种用于样品制备以及在稀水悬浮液中使用批式动态光散射（DLS）测定纳米颗粒平均尺寸（流体动力学直径）的方法。然后，我们针对30 nm胶体金演示了该方法。
