Shen Meixiao, Wang Michael R, Yuan Yimin, Chen Feng, Karp Carol L, Yoo Sonia H, Wang Jianhua
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, 1638 NW 10th Avenue, Miami, FL 33136, USA.
Ophthalmic Surg Lasers Imaging. 2010 Nov-Dec;41 Suppl:S65-9. doi: 10.3928/15428877-20101031-18.
An 840-nm wavelength spectral domain optical coherence tomography (SD-OCT) with prolonged scan depth was developed and mounted onto a conventional slit lamp for imaging the anterior segment of the eye. X-Y cross aiming was applied to align the SD-OCT scanning position during imaging. An internal fixation target displayed on a miniature LCD monitor was provided. The SD-OCT instrument had an axial resolution of 6 μm and a prolonged scan depth of 7.2 mm. High-quality SD-OCT images, consisting of 2,048 × 2,048 pixels, were acquired of the entire anterior chamber and entire crystalline lens from a healthy subject. The entire cornea, anterior chamber angle, limbus, and iris were clearly visible. Additionally, the internal structure of crystalline lens, including anterior and posterior surfaces of the crystalline lens, capsule, nucleus, and cortex, were clearly imaged with the instrument. The system was also tested in imaging accommodation of the same eye, demonstrating the feasibility of the novel approach for evaluating presbyopia/accommodation.
开发了一种具有延长扫描深度的840纳米波长光谱域光学相干断层扫描（SD-OCT），并将其安装在传统裂隙灯上，用于对眼前节进行成像。在成像过程中应用X-Y交叉瞄准来对准SD-OCT扫描位置。提供了一个显示在微型液晶显示器上的内部固定目标。该SD-OCT仪器的轴向分辨率为6微米，扫描深度延长至7.2毫米。从一名健康受试者获取了由2048×2048像素组成的整个前房和整个晶状体的高质量SD-OCT图像。整个角膜、前房角、角膜缘和虹膜清晰可见。此外，该仪器还清晰地成像了晶状体的内部结构，包括晶状体的前表面和后表面、囊膜、核和皮质。该系统还对同一只眼睛的调节进行了成像测试，证明了这种评估老花眼/调节功能的新方法的可行性。
