Department of Clinical Sciences L. Sacco, Faculty of Medicine and Surgery, University of Milan, Milan, Italy.
Int J Food Sci Nutr. 2011 Mar;62(2):175-84. doi: 10.3109/09637486.2010.529068. Epub 2010 Dec 1.
Aqueous and methanol extracts of dry sage, rosemary, basil, parsley, chili, garlic and onion were analyzed to investigate their anti-oxidant and anti-glycant activities and in vitro inhibitory potential against enzymes involved in glycemic regulation. The aqueous extracts of rosemary and sage were the richest in phenolic compounds and showed the highest ability in binding iron and inhibiting DPPH, superoxide radicals and advanced glycation end-product production, lipid peroxidation, and the activity of α-glucosidase and α-amylase. On the other hand, the methanol extracts of both these Labiatae were less efficient than those of garlic, onion, parsley and chili in scavenging hydroxyl radicals. As far as protein glycation is concerned, methanol extracts were more effective in inhibiting the production of Amadori compounds and the aqueous ones in preventing advanced glycation end-product formation. Therefore these spices may be preventive not only against cardiovascular diseases but also type 2 diabetes.
干鼠尾草、迷迭香、罗勒、欧芹、辣椒、大蒜和洋葱的水提物和甲醇提取物进行了分析，以研究它们的抗氧化和抗糖化活性，以及体外对参与血糖调节的酶的抑制潜力。迷迭香和鼠尾草的水提取物含有最丰富的酚类化合物，具有最强的结合铁和抑制 DPPH、超氧自由基和晚期糖基化终产物生成、脂质过氧化以及α-葡萄糖苷酶和α-淀粉酶活性的能力。另一方面，这两种唇形科植物的甲醇提取物在清除羟基自由基方面的效率低于大蒜、洋葱、欧芹和辣椒的提取物。就蛋白质糖化而言，甲醇提取物在抑制 Amadori 化合物的产生方面更有效，而水提取物在防止晚期糖基化终产物形成方面更有效。因此，这些香料不仅可能预防心血管疾病，还可能预防 2 型糖尿病。
