Gandhi Jatin S, Mehta Anurag, Sharma Anila, Kamboj Meenakshi
Department of Histopathology, Rajiv Gandhi Cancer Institute & Research Centre, Rohini, Delhi 110085, India.
J Cancer Res Ther. 2010 Jul-Sep;6(3):342-3. doi: 10.4103/0973-1482.73354.
Primary classical Hodgkin lymphomas of the gastrointestinal tract are rare lymphoproliferative neoplasms as against other well established mucosa-associated lymphoid tissue (MALT) lymphomas. The primary nature of these cases is established based on chest radiograph, computed axial tomography, positron emission tomography, peripheral blood and bone marrow biopsy examination. Here, we report a 79-year-old male patient, who presented to the emergency department with complaints of abdominal discomfort on right side and low grade fever. An ultrasonogram was performed which suggested of an intestinal perforation. An emergency laporotomy was done with resection of the ileal segment. The histomorphology of the resected ileal segment revealed features of classical Hodgkin lymphoma which were confirmed by immunohistochemistry. Epstein Barr virus encoded RNA (EBER) via in-situ hybridization was positive and provided substantial evidence of EBV etiology.
与其他公认的黏膜相关淋巴组织（MALT）淋巴瘤相比，原发性胃肠道经典型霍奇金淋巴瘤是罕见的淋巴增殖性肿瘤。这些病例的原发性是根据胸部X光片、计算机断层扫描、正电子发射断层扫描、外周血和骨髓活检检查来确定的。在此，我们报告一名79岁男性患者，他因右侧腹部不适和低热到急诊科就诊。进行了超声检查，提示肠穿孔。急诊行剖腹探查术，切除回肠段。切除的回肠段组织形态学显示为经典型霍奇金淋巴瘤特征，免疫组化予以证实。原位杂交检测爱泼斯坦-巴尔病毒编码RNA（EBER）呈阳性，为EBV病因提供了充分证据。
