• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Hand pattern indicates prostate cancer risk.手纹提示前列腺癌风险。
Br J Cancer. 2011 Jan 4;104(1):175-7. doi: 10.1038/sj.bjc.6605986. Epub 2010 Nov 30.
2
Comparison of digit ratio (2D:4D) between Brazilian men with and without prostate cancer.患有前列腺癌和未患前列腺癌的巴西男性之间的指长比（2D:4D）比较。
Prostate Cancer Prostatic Dis. 2016 Mar;19(1):107-10. doi: 10.1038/pcan.2015.62. Epub 2016 Jan 12.
3
Second to fourth digit ratio (2D:4D) and prostate cancer risk in the Melbourne Collaborative Cohort Study.第二至第四指骨长度比（2D:4D）与墨尔本协作队列研究中的前列腺癌风险。
Br J Cancer. 2011 Jul 26;105(3):438-40. doi: 10.1038/bjc.2011.253. Epub 2011 Jul 5.
4
2D:4D digit ratio as a potential marker for prostate cancer risk.2D:4D 数字比例作为前列腺癌风险的潜在标志物。
Cancer Epidemiol. 2024 Oct;92:102635. doi: 10.1016/j.canep.2024.102635. Epub 2024 Jul 30.
5
Does the index-to-ring finger length ratio (2D:4D) differ in amyotrophic lateral sclerosis (ALS)? Results from an international online case-control study.肌萎缩侧索硬化症（ALS）患者的食指与无名指长度比（2D:4D）是否存在差异？一项国际在线病例对照研究的结果。
BMJ Open. 2017 Aug 7;7(8):e016924. doi: 10.1136/bmjopen-2017-016924.
6
Digit ratios and relation to myocardial infarction in Greek men and women.希腊男性和女性的指长比及其与心肌梗死的关系。
Gend Med. 2010 Dec;7(6):628-36. doi: 10.1016/j.genm.2010.11.008.
7
Female digit length ratio (2D:4D) and time-to-pregnancy.女性手指长度比例（2D:4D）与受孕时间。
Hum Reprod. 2016 Sep;31(9):2128-34. doi: 10.1093/humrep/dew164. Epub 2016 Jun 23.
8
Second to fourth digit ratio, body mass index, waist-to-hip ratio, and waist-to-chest ratio: their relationships in heterosexual men and women.食指与无名指长度比、体重指数、腰臀比和腰胸比：它们在异性恋男性和女性中的关系。
Ann Hum Biol. 2003 Nov-Dec;30(6):728-38. doi: 10.1080/03014460310001620153.
9
Alternative Digit Ratios and Their Relationship to Prostate Cancer.不同手指比例及其与前列腺癌的关系。
Clin Genitourin Cancer. 2016 Apr;14(2):149-52. doi: 10.1016/j.clgc.2015.11.005. Epub 2015 Nov 12.
10
From palmistry to anthropometry: can 2nd to 4th digit length (2D:4D) predict the risk of prostate cancer?从手相术到人体测量学：食指与无名指长度之比（2D:4D）能否预测前列腺癌风险？
Urol Int. 2014;93(3):257-61. doi: 10.1159/000354275. Epub 2013 Dec 7.

引用本文的文献

1
Digit ratio (2D:4D), laryngeal cancer and vocal fold leukoplakia.指长比（2D:4D）、喉癌与声带白斑
J Cancer Res Clin Oncol. 2023 Sep;149(11):9349-9359. doi: 10.1007/s00432-023-04850-8. Epub 2023 May 21.
2
Are the digit ratio (2D:4D) and hand grip strength related to Parkinson disease in elderly males?老年男性的指长比（2D:4D）和握力与帕金森病有关吗？
BMC Sports Sci Med Rehabil. 2023 Mar 20;15(1):34. doi: 10.1186/s13102-023-00642-2.
3
Prenatal oestrogen-testosterone balance as a risk factor of migraine in adults.产前雌激素-睾丸素平衡作为成年人偏头痛的一个风险因素。
J Headache Pain. 2021 Oct 7;22(1):119. doi: 10.1186/s10194-021-01326-3.
4
Second-to-Fourth Digit Ratio (2D:4D) in Psychiatric Disorders: A Systematic Review of Case-control Studies.精神疾病中的食指与无名指长度比（2D:4D）：病例对照研究的系统评价
Clin Psychopharmacol Neurosci. 2021 Feb 28;19(1):26-45. doi: 10.9758/cpn.2021.19.1.26.
5
The Association of Digit Ratio (2D : 4D) with Cancer: A Systematic Review and Meta-Analysis.指长比（2D:4D）与癌症的关系：系统评价和荟萃分析。
Dis Markers. 2018 Feb 8;2018:7698193. doi: 10.1155/2018/7698193. eCollection 2018.
6
Epigenome-based cancer risk prediction: rationale, opportunities and challenges.基于表观基因组的癌症风险预测：原理、机遇与挑战。
Nat Rev Clin Oncol. 2018 May;15(5):292-309. doi: 10.1038/nrclinonc.2018.30. Epub 2018 Feb 27.
7
Clinical Application of Mathematical Long Bone Ratios to Calculate Appropriate Donor Limb Lengths in Bilateral Upper Limb Transplantation.数学长骨比率在双侧上肢移植中计算合适供体肢体长度的临床应用
Hand (N Y). 2019 Jul;14(4):523-529. doi: 10.1177/1558944717753672. Epub 2018 Jan 24.
8
Low second to fourth digit ratio in Dupuytren disease.掌腱膜挛缩症患者的第二至第四指比例较低。
Medicine (Baltimore). 2017 Aug;96(33):e7801. doi: 10.1097/MD.0000000000007801.
9
Prognostic significance of the digit ratio after hormone therapy for prostate cancer: a prospective multicenter study.激素治疗前列腺癌后 digit 比值的预后意义：一项前瞻性多中心研究。
Sci Rep. 2017 Jul 12;7(1):5229. doi: 10.1038/s41598-017-05638-w.
10
Comparison of digit ratio (2D:4D) between Brazilian men with and without prostate cancer.患有前列腺癌和未患前列腺癌的巴西男性之间的指长比（2D:4D）比较。
Prostate Cancer Prostatic Dis. 2016 Mar;19(1):107-10. doi: 10.1038/pcan.2015.62. Epub 2016 Jan 12.

本文引用的文献

1
Second to fourth digit ratio: a predictor of prostate-specific antigen level and the presence of prostate cancer.第二至第四指比率：前列腺特异性抗原水平和前列腺癌存在的预测指标。
BJU Int. 2011 Feb;107(4):591-6. doi: 10.1111/j.1464-410X.2010.09490.x.
2
Index to ring finger length ratio and the risk of osteoarthritis.无名指长度比与骨关节炎风险索引
Arthritis Rheum. 2008 Jan;58(1):137-44. doi: 10.1002/art.23237.
3
Genetic and environmental influences on 2D:4D finger length ratios: a study of monozygotic and dizygotic male and female twins.遗传和环境对2D:4D指长比的影响：一项对同卵和异卵双胞胎男性及女性的研究。
Arch Sex Behav. 2008 Feb;37(1):112-8. doi: 10.1007/s10508-007-9272-2.
4
A comparison of finger 2D:4D by self-report direct measurement and experimenter measurement from photocopy: methodological issues.通过自我报告直接测量和从复印件进行实验者测量对食指2D:4D进行比较：方法学问题。
Arch Sex Behav. 2009 Feb;38(1):143-8. doi: 10.1007/s10508-007-9202-3. Epub 2007 Jul 26.
5
Evidence for assortative mating on digit ratio (2D:4D), a biomarker for prenatal androgen exposure.关于指长比（2D:4D）存在选型交配的证据，指长比是产前雄激素暴露的生物标志物。
J Biosoc Sci. 2007 Jul;39(4):599-612. doi: 10.1017/S0021932006001647. Epub 2006 Oct 20.
6
Heritability of the second to fourth digit ratio (2d:4d): A twin study.食指与无名指长度比（2d:4d）的遗传力：一项双胞胎研究。
Twin Res Hum Genet. 2006 Apr;9(2):215-9. doi: 10.1375/183242706776382491.
7
A prospective study of plasma selenium levels and prostate cancer risk.血浆硒水平与前列腺癌风险的前瞻性研究。
J Natl Cancer Inst. 2004 May 5;96(9):696-703. doi: 10.1093/jnci/djh125.
8
2nd to 4th digit ratios, fetal testosterone and estradiol.食指与无名指长度比例、胎儿睾酮和雌二醇。
Early Hum Dev. 2004 Apr;77(1-2):23-8. doi: 10.1016/j.earlhumdev.2003.12.002.
9
Finger and toe ratios in humans and mice: implications for the aetiology of diseases influenced by HOX genes.人类和小鼠的指趾比例：对受HOX基因影响的疾病病因学的启示。
Med Hypotheses. 2003 Mar;60(3):340-3. doi: 10.1016/s0306-9877(02)00400-0.
10
2nd to 4th digit ratio and offspring sex ratio.食指与无名指长度比例和后代性别比例。
J Theor Biol. 2002 Jul 7;217(1):93-5. doi: 10.1006/jtbi.2002.3014.

手纹提示前列腺癌风险。

Hand pattern indicates prostate cancer risk.

机构信息

Division of Epidemiology and Public Health, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK.

出版信息

Br J Cancer. 2011 Jan 4;104(1):175-7. doi: 10.1038/sj.bjc.6605986. Epub 2010 Nov 30.

DOI:10.1038/sj.bjc.6605986
PMID:21119657
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3039824/
Abstract

BACKGROUND

The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels.

METHODS

We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls.

RESULTS

Compared with index finger shorter than ring finger (low 2D : 4D), men with index finger longer than ring finger (high 2D : 4D) showed a negative association, suggesting a protective effect with a 33% risk reduction (odds ratio (OR) 0.67, 95% confidence interval (CI) 0.57-0.80). Risk reduction was even greater (87%) in age group <60 (OR 0.13, 95% CI 0.09-0.21).

CONCLUSION

Pattern of finger lengths may be a simple marker of prostate cancer risk, with length of 2D greater than 4D suggestive of lower risk.

摘要

背景

手指长度比例在子宫内就已固定，可能是产前睾酮水平的替代指标。

方法

我们分析了 1524 例前列腺癌病例和 3044 例基于人群的对照者的右手模式与前列腺癌风险。

结果

与食指短于无名指（2D：4D 比值低）相比，食指长于无名指（2D：4D 比值高）的男性表现出负相关，表明存在保护作用，风险降低 33%（比值比 (OR) 0.67，95%置信区间 (CI) 0.57-0.80）。在<60 岁年龄组中，风险降低更为显著（87%）（OR 0.13，95% CI 0.09-0.21）。

结论

手指长度模式可能是前列腺癌风险的简单标志物，2D 长度大于 4D 提示风险较低。