来自海洋海绵莫尔顿索拉氏海绵的两种A环芳构化胆汁酸。
Two ring-A-aromatized bile acids from the marine sponge Sollasella moretonensis.
作者信息
Lu Zhenyu, Van Wagoner Ryan M, Harper Mary Kay, Hooper John N A, Ireland Chris M
机构信息
Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA.
出版信息
Nat Prod Commun. 2010 Oct;5(10):1571-4.
Abstract
Two ring-A-aromatized bile acids, 1 and 2, were isolated from the sponge Sollasella moretonensis, collected from the seabed of northern Queensland. Structures were assigned on the basis of extensive 1D and 2D NMR studies, as well as analysis by HRESIMS. Compound 2 has previously been produced synthetically, though this marks its first isolation from a natural source.
摘要
从昆士兰北部海床采集的莫雷顿索拉海绵中分离出两种A环芳构化胆汁酸1和2。通过广泛的一维和二维核磁共振研究以及高分辨电喷雾电离质谱分析确定了其结构。化合物2此前已通过合成方法制备，但这是首次从天然来源中分离得到。
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