Chaplin M F
Food Research Centre, South Bank University, London.
J R Soc Health. 1998 Feb;118(1):53-61. doi: 10.1177/146642409811800111.
Are the changes in faecal bile acid concentrations the cause of colorectal cancer or one of its effects? This is an area of controversy mainly due to the lack of a clear explanation as to how the bile acid concentrations are controlled under different circumstances. This review presents an outline of the evidence that bile acids are both a causal factor in colorectal cancer and that their concentrations are affected by it in a synergistic manner. It also offers an explanation of how some dietary fibre protects against colorectal cancer.
粪便胆汁酸浓度的变化是结直肠癌的病因还是其结果之一？这是一个存在争议的领域，主要是因为缺乏关于在不同情况下胆汁酸浓度如何受到控制的明确解释。本综述概述了胆汁酸既是结直肠癌的致病因素，且其浓度又会以协同方式受到结直肠癌影响的证据。它还解释了某些膳食纤维如何预防结直肠癌。
