Department of Neurology, Justus-Liebig-University, Giessen, Germany.
J Neuroimaging. 2012 Jan;22(1):42-5. doi: 10.1111/j.1552-6569.2010.00546.x. Epub 2010 Dec 1.
The use of an ultrasound-based evaluation of the optic nerve sheath diameter (ONSD) has previously been demonstrated for detecting raised intracranial pressure. In order to be feasible in clinical workup, the test qualities of transorbital ultrasonography need to be determined. The aim of this study was therefore to establish normal values and to assess the intra- and interobserver reliability of this method.
Using a 9-3 MHz linear array transducer, the ONSD of 40 healthy subjects was independently measured by 2 investigators.
Depicting the optic nerve and its sheath was possible in all individuals. The mean ONSD was 5.4 ± .6 mm with a range of 4.3-7.6 mm. The intraobserver reliability analyzed with Cronbach's Alpha was found to be high with values between .92 and .97. Pearson's correlation coefficient between the 2 investigators was .81 on the right side and .84 on the left. There was no correlation between ONSD and age, body mass index, or gender.
Transorbital B-mode sonography is a feasible method to assess the ONSD with a high intra- and interobsever reliability. Normal values on ONSD are presented in this study that will be useful in future studies on pathological conditions.
经超声评估视神经鞘直径（ONSD）已被证实可用于检测颅内压升高。为了使其在临床评估中可行，需要确定经眶超声检查的测试质量。因此，本研究旨在确定正常范围，并评估该方法的观察者内和观察者间可靠性。
使用 9-3MHz 线性阵列换能器，由 2 名研究者独立测量 40 名健康受试者的 ONSD。
所有个体均能清晰显示视神经及其鞘。平均 ONSD 为 5.4±0.6mm，范围为 4.3-7.6mm。用 Cronbach's Alpha 分析观察者内可靠性，值在.92 到.97 之间，结果显示可靠性较高。右侧观察者间 Pearson 相关系数为.81，左侧为.84。ONSD 与年龄、体重指数或性别无相关性。
经眶 B 型超声是一种评估 ONSD 的可行方法，具有较高的观察者内和观察者间可靠性。本研究提出了 ONSD 的正常范围，这将对未来病理性疾病的研究有用。
