Scholtes G
Geburtshilfe Frauenheilkd. 1977 Sep;37(9):747-55.
The fetal prognosis in multiple pregnancies can be improved by a multifaceted antenatal program which includes early diagnosis prior to 28 weeks gestation, follow-up of multiple pregnancies in the high risk antenatal clinic, early discontinuation of work, treatment of pre-eclampsia, bed rest in hospital between 28 and 33 weeks and sometimes cerclage, prophylactic and therapeutic administration of labour inhibiting drugs, speedy delivery of the second twin and immediate pediatric care. Bed rest and administration of labour inhibiting drugs are the most important points of this program. With this combination, the utero-placental perfusion can be improved. The gestation can be prolonged and the incidence of small weight neonates and the incidence of the perinatal mortality can be reduced. Since even a large antenatal clinic only cares for a small number of multiple pregnancies, a multicentre study to determine the optimal management of multiple pregnancies is urgently required. Multiple pregnancies had too little attention in modern perinatal medicine and deserve all our attention for an improvement of their outcome.
多胎妊娠的胎儿预后可通过多方面的产前计划得到改善,该计划包括在妊娠28周前进行早期诊断、在高危产前诊所对多胎妊娠进行随访、尽早停止工作、治疗子痫前期、在28至33周期间住院卧床休息,有时还包括宫颈环扎术、预防性和治疗性使用抑制宫缩的药物、尽快娩出第二个胎儿以及立即进行儿科护理。卧床休息和使用抑制宫缩的药物是该计划的最重要要点。通过这种联合措施,可以改善子宫胎盘灌注。可延长妊娠期,并降低低体重新生儿的发生率和围产期死亡率。由于即使是大型产前诊所也只照料少数多胎妊娠病例,因此迫切需要开展一项多中心研究,以确定多胎妊娠的最佳管理方法。多胎妊娠在现代围产医学中受到的关注太少,为改善其结局值得我们给予充分关注。