Infection Control Program, Geneva University Hospitals and Medical School, 4 rue G-P-G, CH-1211 Geneva 14, Switzerland.
Crit Care. 2010;14(6):240. doi: 10.1186/cc9268. Epub 2010 Nov 5.
In 2009 Critical Care provided important and clinically relevant research data for management and prevention of infections in critically ill patients. The present review summarises the results of these observational studies and clinical trials and discusses them in the context of the current relevant scientific and clinical background. In particular, we discuss recent epidemiologic data on nosocomial infections in intensive care units, present new approaches to prevention of ventilator-associated pneumonia, describe recent advances in biomarker-guided antibiotic stewardship and attempt to briefly summarise specific challenges related to the management of infections caused by multidrug-resistant microorganisms and influenza A (H1N1).
2009 年,《危重病医学》为重症患者感染的管理和预防提供了重要的、具有临床相关性的研究数据。本综述总结了这些观察性研究和临床试验的结果,并结合当前相关的科学和临床背景对其进行了讨论。特别地,我们讨论了重症监护病房医院获得性感染的最新流行病学数据,提出了预防呼吸机相关性肺炎的新方法,描述了生物标志物指导下抗生素管理的最新进展,并尝试简要总结与多药耐药微生物和甲型 H1N1 流感引起的感染管理相关的具体挑战。