Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Qual Life Res. 2011 May;20(4):529-35. doi: 10.1007/s11136-010-9786-2. Epub 2010 Dec 3.
We evaluated the reliability and validity of the Pediatric Functional Assessment of Cancer Therapy-Childhood Brain Tumor Survivor version 2.0 (pedsFACT-BrS; patient version for grade school children aged 7-12 years).
After translating and cross-culturally adapting it into Korean, the psychometric properties of the pedsFACT-BrS were evaluated in 148 childhood brain tumor survivors (mean age, 9.67 years). Pre-testing was performed in 25 patients.
The pedsFACT-BrS showed good symptom coverage and overall user comprehension. Internal consistency was acceptable, with Cronbach's α coefficients ranging from 0.70 to 0.92. The pedsFACT-BrS also demonstrated good convergent and divergent validities when correlated with the Revised Children's Manifest Anxiety Scale and Kovacs' Children's Depression Scale. The pedsFACT-BrS showed good known-group validity and effectively differentiated between clinically distinct patient groups (patient vs. control groups, and among patients having different Karnofsky scores), but offered only partial discrimination of physical well-being (PWB) scores when patients were grouped by treatment type.
Our results indicate that this instrument is reliable and valid and can be used to evaluate the quality of life of Korean childhood brain tumor survivors.
我们评估了儿科癌症治疗功能评估-儿童脑肿瘤幸存者版本 2.0(pedsFACT-BrS;适用于 7-12 岁小学生的患者版本)的可靠性和有效性。
在将其翻译成韩语并进行跨文化适应性调整后,我们在 148 名儿童脑肿瘤幸存者(平均年龄为 9.67 岁)中评估了 pedsFACT-BrS 的心理测量特性。对 25 名患者进行了预测试。
pedsFACT-BrS 表现出良好的症状涵盖范围和整体用户理解能力。内部一致性可接受,Cronbach's α 系数范围为 0.70 至 0.92。pedsFACT-BrS 与修订后的儿童 manifest 焦虑量表和 Kovacs 的儿童抑郁量表相关时,也表现出良好的收敛和发散有效性。pedsFACT-BrS 具有良好的已知组有效性,并能有效区分临床不同的患者组(患者与对照组,以及具有不同 Karnofsky 评分的患者之间),但在按治疗类型分组时,对身体幸福感(PWB)评分的区分度仅为部分。
我们的结果表明,该工具具有可靠性和有效性,可用于评估韩国儿童脑肿瘤幸存者的生活质量。