Sloan Jeff A, Frost Marlene H, Berzon Rick, Dueck Amylou, Guyatt Gordon, Moinpour Carol, Sprangers Mirjam, Ferrans Carol, Cella David
Department of Health Sciences Research, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA.
Support Care Cancer. 2006 Oct;14(10):988-98. doi: 10.1007/s00520-006-0085-y. Epub 2006 Jun 23.
A series of six manuscripts with an introduction appeared in the Mayo Clinic Proceedings, based upon the collective effort of 30 individuals with an interest and expertise in assessing the clinical significance of quality of life (QOL) assessments. The series of manuscripts described the state of the science of QOL assessments in oncology clinical research and practice and included extensive literature and theoretical justification for the continued inclusion of QOL in oncology clinical research and practice.
The purpose of this paper is to produce a summary of these articles and to supplement these works with additional information that was gleaned from subsequent meetings and discussions of this material. The primary aim of this paper is to present a cogent and concise description for clinicians to facilitate the incorporation of QOL assessments into oncology clinical research and practice. The theoretical discussion is supplemented with an example of how the various ideas can be operationalized in an oncology clinical trial.
《梅奥诊所学报》发表了一系列共六篇配有引言的手稿，这些手稿是由30位对评估生活质量（QOL）评估的临床意义感兴趣且具备专业知识的人员共同努力完成的。该系列手稿描述了肿瘤临床研究与实践中生活质量评估的科学现状，包括将生活质量持续纳入肿瘤临床研究与实践的大量文献及理论依据。
本文旨在总结这些文章，并通过从后续对此材料的会议和讨论中收集的额外信息对这些作品进行补充。本文的主要目的是为临床医生提供一个有说服力且简洁的描述，以促进将生活质量评估纳入肿瘤临床研究与实践。理论讨论辅以一个示例，说明各种理念如何在肿瘤临床试验中得以实施。
