来自神香草全草的两种新黄酮苷。

Two new flavonoid glycosides from the whole herbs of Hyssopus officinalis.

作者信息

Wang Nan, Yang Xiu-Wei

机构信息

State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing, China.

出版信息

J Asian Nat Prod Res. 2010 Dec;12(12):1044-50. doi: 10.1080/10286020.2010.533120.

DOI:10.1080/10286020.2010.533120

PMID:21128145

Abstract

Two new flavonoid glycosides, quercetin 7-O-β-D-apiofuranosyl-(1 → 2)-β-D-xylopyranoside (1) and quercetin 7-O-β-D-apiofuranosyl-(1 → 2)-β-D-xylopyranoside 3'-O-β-D-glucopyranoside (2), together with nine known flavonoids were isolated from the whole herbs of Hyssopus officinalis L. cultivated in Xinjiang Uygur Autonomous Region of China. All structures were characterized by the spectroscopic methods including UV, IR, ESI-MS, 1D, and 2D NMR. Their potent free radical scavenging activity against the stable 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical was evaluated.

摘要

从中国新疆维吾尔自治区种植的神香草全草中分离出两种新的黄酮苷，槲皮素7 - O - β - D - 芹菜呋喃糖基 - (1→2) - β - D - 木吡喃糖苷（1）和槲皮素7 - O - β - D - 芹菜呋喃糖基 - (1→2) - β - D - 木吡喃糖苷3'- O - β - D - 葡萄糖苷（2），以及九种已知黄酮类化合物。所有结构均通过包括紫外光谱（UV）、红外光谱（IR）、电喷雾电离质谱（ESI - MS）、一维核磁共振（1D NMR）和二维核磁共振（2D NMR）在内的光谱方法进行表征。评估了它们对稳定的2,2 - 二苯基 - 1 - 苦基肼（DPPH）自由基的强大自由基清除活性。