来自田菜的抗氧化酚苷。

Antioxidant phenolic glycosides from Moricandia arvensis.

作者信息

Braham Hatem, Mighri Zine, Jannet Hichem Ben, Matthew Susan, Abreu Pedro M

机构信息

Laboratoire de Chimie des Substances Naturelles et de Synthèse Organique, Faculté des Sciences de Monastir, 5000 Monastir, Tunisia.

出版信息

J Nat Prod. 2005 Apr;68(4):517-22. doi: 10.1021/np049581m.

DOI:10.1021/np049581m

PMID:15844940

Abstract

The new phenolic glycosides quercetin 3,4'-di-O-beta-d-glucopyranoside-7-O-alpha-l-rhamnopyranoside (moricandin) (1), beta-d-glucopyranosyl 4-O-beta-d-glucopyranosylcaffeate (2), methyl 3-O-beta-d-glucopyranosyl-5-hydroxycinnamate (3), and beta-d-glucopyranosyl 4-O-beta-d-glucopyranosylbenzoate (4), together with the previously known beta-d-glucopyranosyl 4-hydroxybenzoate (5), methyl 4-O-beta-d-glucopyranosylcaffeate (6), 1-O-caffeoyl-beta-d-glucopyranoside (7), and 2-phenylethyl-beta-d-glucopyranoside (8), were isolated from the flowers of Moricandia arvensis. Their structures were elucidated by extensive spectroscopic analysis and chemical methods. Compounds 1-8 were evaluated for antioxidant activity using DPPH, TEAC, and reducing power assays, where the caffeic acid derivative 7 and the quercetin triglycoside 2 proved to possess the most potent scavenging activity.

摘要

从田野滨藜的花中分离出了新的酚苷槲皮素3,4'-二 -O-β -D-吡喃葡萄糖苷 -7-O-α -L-鼠李吡喃糖苷（滨藜苷）（1）、β -D-吡喃葡萄糖基4-O-β -D-吡喃葡萄糖基咖啡酸（2）、3-O-β -D-吡喃葡萄糖基 -5-羟基肉桂酸甲酯（3）和β -D-吡喃葡萄糖基4-O-β -D-吡喃葡萄糖基苯甲酸酯（4），以及先前已知的β -D-吡喃葡萄糖基4-羟基苯甲酸（5）、4-O-β -D-吡喃葡萄糖基咖啡酸甲酯（6）、1-O-咖啡酰基-β -D-吡喃葡萄糖苷（7）和2-苯乙基-β -D-吡喃葡萄糖苷（8）。通过广泛的光谱分析和化学方法阐明了它们的结构。使用DPPH、TEAC和还原能力测定法对化合物1 - 8的抗氧化活性进行了评估，其中咖啡酸衍生物7和槲皮素三糖苷2表现出最强的清除活性。