Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, UK.
Heart. 2011 Apr;97(8):655-9. doi: 10.1136/hrt.2010.201012. Epub 2010 Dec 3.
The aim of this study was to investigate the contribution of physical inactivity to the excess mortality from coronary heart disease (CHD) observed in the UK South Asian population.
An observational longitudinal study with follow-up mortality data from NHS registries.
Data from the Health Survey for England, 1999 and 2004.
13 293 White and 2120 South Asian participants aged ≥35 years consented to the mortality follow-up.
Deaths from CHD.
South Asian participants were more likely to be physically inactive than white participants (47.0% vs 28.1%). Deaths from CHD were more common in UK South Asian participants, particularly among Pakistani and Bangladeshi groups (HR 2.87, 95% CI 1.74 to 4.73), than in UK white participants, and South Asian people experienced an event at an age on average 10 years younger than white people. Physical inactivity explained >20% of the excess CHD mortality in the South Asian sample, even after adjustment for potential confounding variables (including socioeconomic position, smoking, diabetes and existing cardiovascular disease).
Physical inactivity makes a significant contribution to the excess CHD mortality observed in the South Asian population in the UK. This highlights the importance of prioritising the promotion of physical activity in this high-risk population.
本研究旨在探讨身体活动不足对英国南亚人群冠心病(CHD)超额死亡率的影响。
一项观察性纵向研究,随访来自国民保健署登记处的死亡率数据。
英格兰健康调查,1999 年和 2004 年的数据。
年龄≥35 岁并同意进行死亡率随访的 13293 名白人和 2120 名南亚参与者。
CHD 死亡。
南亚参与者比白人参与者更可能不活跃(47.0%比 28.1%)。英国南亚参与者的 CHD 死亡更为常见,尤其是在巴基斯坦和孟加拉国人群中(HR 2.87,95%CI 1.74 至 4.73),而英国白人参与者则较少,南亚人经历 CHD 事件的平均年龄比白人年轻 10 岁。即使在调整了潜在混杂变量(包括社会经济地位、吸烟、糖尿病和现有心血管疾病)后,身体活动不足仍解释了南亚人群中超过 20%的 CHD 死亡超额。
身体活动不足对英国南亚人群中观察到的 CHD 死亡超额有重要贡献。这突显了在这一高风险人群中优先促进身体活动的重要性。