Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
Int J Gynecol Pathol. 2011 Jan;30(1):36-40. doi: 10.1097/PGP.0b013e3181f45f28.
Interpretation of the mucinous change in the fallopian tubes has been difficult because several reports consider this mucinous change as a metastasis from a mucinous tumor. To clarify this issue, we decided to retrospectively review salpingectomies from 3 institutions looking for mucinous change in the fallopian tubes and documented the clinical history of these patients. Twenty-three cases of fallopian tubes with mucinous changes were found, including 11 patients without evidence of malignancy, 4 patients with mucinous ovarian tumors, 5 patients with nonmucinous gynecologic tumors, 2 patients with mucinous appendiceal neoplasm, and 1 patient with colon carcinoma. As mucinous changes are seen in several patients who do not have a malignant tumor, we believe that these changes represent a metaplastic process. The mucinous changes are frequently seen with chronic inflammation and/or other metaplastic changes and without cytologic evidence of malignancy.
输卵管黏液性改变的解释一直很困难，因为有几个报道认为这种黏液性改变是黏液性肿瘤的转移。为了澄清这个问题，我们决定回顾性地检查 3 个机构的输卵管切除术，寻找输卵管的黏液性改变，并记录这些患者的临床病史。发现 23 例输卵管有黏液性改变，其中 11 例无恶性肿瘤证据，4 例有黏液性卵巢肿瘤，5 例有非黏液性妇科肿瘤，2 例有阑尾黏液性肿瘤，1 例有结肠癌。由于有几个没有恶性肿瘤的患者有黏液性改变，我们认为这些改变代表一种化生过程。这些黏液性改变常与慢性炎症和/或其他化生改变一起出现，且没有细胞学恶性证据。
