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作者信息

Chávez Natividad, Molina Helfer, Sánchez Jorge, Gelaye Bizu, Sánchez Sixto E

机构信息

Departamento de Epidemiología, Programa de Entrenamiento Internacional de Investigación Multidisciplinario, Universidad de Washington - Escuela de Salud Publica y Medicina Comunitaria, Seattle, Washington, USA.

出版信息

Rev Peru Med Exp Salud Publica. 2009 Jan 1;26(3):299-306.

Abstract

OBJECTIVE

Bacterial vaginosis (BV) is an infection characterized by a change in the micro flora of the vagina. BV has been associated with adverse pregnancy outcomes and increased risk of acquisitions of sexually transmitted diseases (STD). In this study, we sought to determine the association of douching and other behavioral risk factors in relation to BV. METHODS: This cross-sectional study was carried out among 1252 women attending four family planning clinics in Lima, Peru in 1997. Structured questionnaire was used to collect information on socio-demographic and lifestyle characteristics of women. BV was diagnosed by the Nugent's score. Logistic regression procedures were employed to estimate adjusted odds ratios (OR) and 95% confidence intervals (95% CI). RESULTS: Mean age of participants was 25.1 ± 4.7 and 23.4% had more than 11 years of formal education. The prevalence of BV was 20.1% and significantly associated with a number of behavioral risk factors. Women who practice douching were 2.28-times (OR=2.28; 95% CI: 1.0-5.0) more likely to have BV compared with those who didn't practice. Having two or more sexual partners was also associated with a two folds (OR=2.0; 95% CI: 1.2-3.5) increased risk of BV. Those who started sexual intercourse at a younger age were 1.4-times (OR=1.0-1.9) more likely to have BV. CONCLUSION AND IMPLICATION: Douching is a risk factors associated with BV among Peruvian women. Programs aimed at women's health must address the adverse health outcomes associated with douching. Future population based studies that investigate associations of douching and adverse reproductive and gynecologic health outcomes need to be conducted.

摘要

目的

细菌性阴道病(BV)是一种以阴道微生物群变化为特征的感染。BV与不良妊娠结局及性传播疾病(STD)感染风险增加有关。在本研究中,我们试图确定灌洗及其他行为危险因素与BV的关联。

方法

1997年,在秘鲁利马的四家计划生育诊所对1252名女性进行了这项横断面研究。采用结构化问卷收集女性的社会人口学和生活方式特征信息。通过Nugent评分诊断BV。采用逻辑回归程序估计调整后的比值比(OR)和95%置信区间(95%CI)。

结果

参与者的平均年龄为25.1±4.7岁,23.4%的人接受过11年以上的正规教育。BV的患病率为20.1%,且与多种行为危险因素显著相关。与未进行灌洗的女性相比,进行灌洗的女性患BV的可能性高2.28倍(OR=2.28;95%CI:1.0 - 5.0)。有两个或更多性伴侣也与BV风险增加两倍(OR=2.0;95%CI:1.2 - 3.5)有关。那些开始性行为年龄较小的人患BV的可能性高1.4倍(OR=1.0 - 1.9)。

结论及启示

灌洗是秘鲁女性中与BV相关的一个危险因素。针对女性健康的项目必须解决与灌洗相关的不良健康后果。未来需要开展基于人群的研究,调查灌洗与不良生殖和妇科健康结局的关联。

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