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架构即信息:细胞外基质和三维结构在组织特异性基因表达及乳腺癌中的作用

Architecture Is the Message: The role of extracellular matrix and 3-D structure in tissue-specific gene expression and breast cancer.

作者信息

Bissell Mina J

出版信息

Pezcoller Found J. 2007 Oct;16(29):2-17.

Abstract

I was honored to deliver the 2(nd) Stanley Korsmeyer memorial Lecture on May 9(th), 2007 in Padova, Italy. Stan will always occupy a very special place in my heart: I admired him greatly not only for his magnificent and original science but also for his integrity and his grace. This review, which summarizes my laboratory's contribution to cell and cancer biology in the last 30 years, is dedicated to Stan's memory, and to Elaine Fuchs, one of my most cherished friends without whose support this work would not have gained the degree of recognition it enjoys today. My thanks also to the Pezcoller Foundation for making that week in May, 2007 one of the most memorable in my scientific life.

摘要

2007年5月9日,我很荣幸在意大利帕多瓦发表了第二届斯坦利·科斯迈耶纪念讲座。斯坦在我心中永远占据着非常特殊的位置:我非常钦佩他,不仅因为他卓越而独创的科学成就,还因为他的正直和优雅。这篇综述总结了我的实验室在过去30年对细胞和癌症生物学的贡献,谨以此献给斯坦的纪念,也献给伊莱恩·富克斯,她是我最珍视的朋友之一,没有她的支持,这项工作不会获得如今所享有的认可程度。我还要感谢佩兹科勒基金会,让2007年5月的那一周成为我科学人生中最难忘的时光之一。

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