Ali Naeem Sultan, Nawaz Ahmad, Rajput Shaheryar, Ikram Mubasher
Division of Otorhinolaryngology-Head and Neck Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Asian Pac J Cancer Prev. 2010;11(4):1111-3.
The purpose of this study was to analyze the clinical presentation, histopathology and complications following parotid surgery.
We retrospectively reviewed the charts of 112 patients who underwent parotidectomy from January 2000 to February 2010. Data including age, sex, clinical signs and symptoms, histology and complication were collected from medical records.
Of the total, 82 (74%) had benign lesions, 30 (36%) had malignant tumors. The most common benign tumor was pleomorphic adenoma (57%), and the most common malignant tumor was mucoepidermoid carcinoma (16%). Analysis of the correlation between fine-needle aspiration cytology and final histology revealed that fine-needle aspiration sensitivity, specificity and accuracy to 86.6%, 97.6% and 94.6% respectively. The most common complication following parotidectomy was transient facial nerve palsy (18.7%).
Superficial parotidectomy is associated with a decrease incidence of transient facial nerve dysfunction compared with that of total parotidectomy. High grade or advanced tumour is a predictor of poor outcome which may require adjuvant therapy.
本研究旨在分析腮腺手术后的临床表现、组织病理学及并发症情况。
我们回顾性分析了2000年1月至2010年2月期间接受腮腺切除术的112例患者的病历。从医疗记录中收集包括年龄、性别、临床症状和体征、组织学及并发症等数据。
总体而言,82例(74%)为良性病变,30例(36%)为恶性肿瘤。最常见的良性肿瘤是多形性腺瘤(57%),最常见的恶性肿瘤是黏液表皮样癌(16%)。细针穿刺细胞学检查与最终组织学结果的相关性分析显示,细针穿刺的敏感性、特异性和准确性分别为86.6%、97.6%和94.6%。腮腺切除术后最常见的并发症是暂时性面神经麻痹(18.7%)。
与全腮腺切除术相比,浅叶腮腺切除术导致暂时性面神经功能障碍的发生率较低。高级别或晚期肿瘤是预后不良的预测因素,可能需要辅助治疗。