Fungal Cell Biology Group, Institute of Cell Biology, University of Edinburgh, Rutherford Building, Edinburgh EH93JH, UK.
Fungal Genet Biol. 2011 Apr;48(4):388-99. doi: 10.1016/j.fgb.2010.11.009. Epub 2010 Dec 4.
The perithecium of the self-fertile ascomycete Sordaria macrospora provides an excellent model in which to analyse fungal multicellular development. This study provides a detailed analysis of perithecium morphogenesis in the wild type and eight developmental mutants of S. macrospora, using a range of correlative microscopical techniques. Fundamentally, perithecia and other complex multicellular structures produced by fungi arise by hyphal aggregation and adhesion, and these processes are followed by specialization and septation of hyphal compartments within the aggregates. Perithecial morphogenesis can be divided into the ascogonial, protoperithecial, and perithecial stages of development. At least 13 specialized, morphologically distinct cell-types are involved in perithecium morphogenesis, and these fall into three basic classes: hyphae, conglutinate cells and spores. Conglutinate cells arise from hyphal adhesion and certain perithecial hyphae develop from conglutinate cells. Various hypha-conglutinate cell transitions play important roles during the development of the perithecial wall and neck.
自育的子囊菌 Sordaria macrospora 的子囊壳为分析真菌多细胞发育提供了极好的模型。本研究使用一系列相关的显微镜技术，对 S. macrospora 的野生型和 8 种发育突变体的子囊壳形态发生进行了详细分析。从根本上说，子囊壳和真菌产生的其他复杂多细胞结构是通过菌丝聚集和黏附产生的，这些过程之后是聚集物中菌丝隔室的特化和分隔。子囊壳的形态发生可以分为产囊丝、原囊壳和子囊壳发育阶段。至少有 13 种专门的、形态不同的细胞类型参与子囊壳形态发生，这些细胞类型分为 3 个基本类：菌丝、黏合细胞和孢子。黏合细胞是由菌丝黏附产生的，某些子囊壳菌丝是由黏合细胞发育而来的。在子囊壳壁和颈的发育过程中，各种菌丝-黏合细胞的转变起着重要作用。
