The role of phospholipase A2 in lipid peroxidation-induced fall of membrane potential of rat liver mitochondria.
作者信息
Gogvadze V G, Brustovetsky N N, Zhukova A A
机构信息
Institute of Biological Physics, USSR Academy of Sciences, Pushchino.
出版信息
FEBS Lett. 1990 May 21;264(2):168-70. doi: 10.1016/0014-5793(90)80240-j.
PMID:2113483
Abstract
Cumene hydroperoxide (230 microM)-induced fall of the membrane potential takes place only in Ca2(+)-loaded mitochondria. Inhibitor of phospholipase A2 p-bromphenacyl bromide prevents uncoupling of mitochondria, having no effect on the accumulation of lipid peroxidation products.
摘要
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