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脑血管分裂:综述。第二部分:钝性脑血管损伤。

Cerebrovascular dissections: a review. Part II: blunt cerebrovascular injury.

机构信息

Department of Surgery, Division of Neurosurgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.

出版信息

Neurosurgery. 2011 Feb;68(2):517-30; discussion 530. doi: 10.1227/NEU.0b013e3181fe2fda.

Abstract

Traumatic cerebrovascular injury (TCVI) is present in approximately 1% of all blunt force trauma patients and is associated with injuries such as head and cervical spine injuries and thoracic trauma. Increased recognition of patients with TCVI in the past quarter century has been because of aggressive screening protocols and noninvasive imaging with computed tomography angiography. Extracranial carotid and vertebral artery injuries demonstrate a spectrum of severity, from intimal disruption to traumatic aneurysm formation or vessel occlusion. The most common intracranial arterial injuries are carotid-cavernous fistulae and traumatic aneurysms. Data on the long-term natural history of TCVI are limited, and management of patients with TCVI is controversial. Although antithrombotic medical therapy is associated with improved neurological outcomes, the optimal medication regimen is not yet established. Endovascular techniques have become more popular than surgery for the treatment of TCVI; endovascular options include stenting of dissections, intra-arterial thrombolysis for acute ischemic stroke caused by trauma, and embolization of traumatic aneurysms.

摘要

创伤性脑血管损伤(TCVI)约占所有钝器伤患者的 1%,与头部和颈椎损伤以及胸部创伤等损伤有关。在过去的四分之一个世纪中,由于积极的筛查方案和计算机断层血管造影术的无创成像,人们对 TCVI 患者的认识有所提高。颅外颈动脉和椎动脉损伤表现出从内膜破裂到创伤性动脉瘤形成或血管闭塞的一系列严重程度。最常见的颅内动脉损伤是颈动脉海绵窦瘘和创伤性动脉瘤。关于 TCVI 的长期自然病史的数据有限,TCVI 患者的治疗存在争议。尽管抗血栓药物治疗与改善神经功能预后相关,但最佳药物治疗方案尚未确定。血管内技术比手术治疗 TCVI 更为流行;血管内治疗方法包括夹层支架置入、创伤性急性缺血性卒中的动脉内溶栓以及创伤性动脉瘤的栓塞。

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