Drenovska Kossara, Darlenski Razvigor, Kazandjieva Jana, Vassileva Snejina
Department of Dermatology and Venereology, Sofia Faculty of Medicine, Sofia, Bulgaria.
Skinmed. 2010 May-Jun;8(3):144-9.
The management and counseling of patients with pemphigus vulgaris during pregnancy is a challenge. The frequency of the association is very low and the current knowledge is based only on case reports or small series. The authors report 2 cases ofpemphigus vulgaris and pregnancy that differed from each other in the time of occurrence and clinical course but had similar favorable outcomes. Based on a literature review and their personal observations, the authors discuss the characteristics of this association, the therapeutic behavior, patients' followup, and fetal prognosis.
寻常型天疱疮患者孕期的管理与咨询是一项挑战。该病与妊娠相关的发生率非常低,目前的认知仅基于病例报告或小样本系列研究。作者报告了2例寻常型天疱疮合并妊娠的病例,这2例在发病时间和临床过程上有所不同,但均有相似的良好结局。基于文献综述及个人观察,作者探讨了这种关联的特点、治疗措施、患者随访及胎儿预后。