Naval Medical Research Center Detachment, Callao, Peru.
Influenza Other Respir Viruses. 2011 Jan;5(1):1-5. doi: 10.1111/j.1750-2659.2010.00160.x. Epub 2010 Sep 16.
Globally, respiratory infections are the primary cause of illness in developing countries, specifically among children; however, an etiological agent for many of these illnesses is rarely identified.
Our study aimed to estimate the frequency of human bocavirus (HBoV) infection among pediatric populations in Argentina, Nicaragua and Peru.
We conducted a cross-sectional study using stored samples of an influenza-like illness surveillance program. Irrespective of previous diagnosis, nasopharyngeal or nasal swab specimens were randomly selected and tested using real-time PCR from three sites during 2007 from patients younger than 6 years old.
A total of 568 specimens from Argentina (185), Nicaragua (192) and Peru (191) were tested. The prevalence of HBoV was 10·8% (95% CI: 6·3; 15·3) in Argentina, 33·3% in Nicaragua (95% CI: 26·6; 40·1) and 25·1% in Peru (95% CI: 18·9; 31·3).
These findings demonstrate circulation of HBoV in Argentina, Nicaragua and Peru among children with influenza-like symptoms enrolled in a sentinel surveillance program.
在发展中国家，呼吸道感染是导致疾病的主要原因，尤其是在儿童中；然而，这些疾病的许多病原体很少被确定。
我们的研究旨在估计人类博卡病毒（HBoV）在阿根廷、尼加拉瓜和秘鲁儿科人群中的感染频率。
我们进行了一项横断面研究，使用流感样疾病监测计划中储存的样本。在 2007 年期间，从三个地点随机选择了鼻咽或鼻拭子标本，并使用实时 PCR 对来自阿根廷（185 例）、尼加拉瓜（192 例）和秘鲁（191 例）的小于 6 岁的患者进行了检测。
共检测了来自阿根廷（185 例）、尼加拉瓜（192 例）和秘鲁（191 例）的 568 个标本。在阿根廷，HBoV 的患病率为 10.8%（95%CI：6.3；15.3）；在尼加拉瓜为 33.3%（95%CI：26.6；40.1）；在秘鲁为 25.1%（95%CI：18.9；31.3）。
这些发现表明，在流感样症状的哨点监测计划中，HBoV 在阿根廷、尼加拉瓜和秘鲁的儿童中传播。
