一种简单的补充 ω-3 多不饱和脂肪酸的方法：在健康志愿者中使用强化酸奶。
A simple method of supplementation of omega-3 polyunsaturated fatty acids: use of fortified yogurt in healthy volunteers.
机构信息
Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
出版信息
Nutr Clin Pract. 2010 Dec;25(6):641-5. doi: 10.1177/0884533610385699.
Abstract
BACKGROUND
A relative dietary ω-3 fatty acid deficiency exists in Western diets, and this deficiency may be associated with some chronic diseases. The aim of the present study was to supplement yogurt with docosahexaenoic acid and assess whether this fatty acid could be incorporated into plasma lipids.
METHODS
We developed a stable emulsion of docosahexaenoic acid that was incorporated into yogurt. Twelve healthy volunteers agreed to consume 1 serving daily that contained 600 mg of docosahexaenoic acid.
RESULTS
After 3 weeks of supplementation, plasma phospholipid docosahexaenoic acid content increased significantly, by 32%, in parallel with a 16% rise in total ω-3 fatty acids. This result was associated with a significant 7% decline in phospholipid arachidonic acid.
CONCLUSIONS
Fortification of ordinary foods with docosahexaenoic acid is a potentially attractive method of increasing ω-3 fatty acid content of plasma lipids, and might even lower arachidonic acid concentrations.
摘要
背景
西方饮食中相对缺乏ω-3 脂肪酸，这种缺乏可能与一些慢性疾病有关。本研究的目的是在酸奶中添加二十二碳六烯酸，并评估这种脂肪酸是否可以被纳入血浆脂质。
方法
我们开发了一种稳定的二十二碳六烯酸乳液，将其加入酸奶中。12 名健康志愿者同意每天食用 1 份含有 600 毫克二十二碳六烯酸的酸奶。
结果
补充 3 周后，血浆磷脂二十二碳六烯酸含量显著增加 32%，同时总 ω-3 脂肪酸增加 16%。这一结果与磷脂花生四烯酸显著下降 7%有关。
结论
用二十二碳六烯酸强化普通食品是增加血浆脂质中 ω-3 脂肪酸含量的一种潜在有吸引力的方法，甚至可能降低花生四烯酸的浓度。
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