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黏膜相关淋巴组织淋巴瘤与前列腺同时性腺癌

Mucosa-associated lymphoid tissue lymphoma and concurrent adenocarcinoma of the prostate.

作者信息

Kang Jung Julie, Eaton Michael S, Ma Yanling, Streeter Oscar, Kumar Parvesh

出版信息

Rare Tumors. 2010 Sep 30;2(3):e54. doi: 10.4081/rt.2010.e54.

DOI:10.4081/rt.2010.e54
PMID:21139969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2994529/
Abstract

Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the prostate is a rare disease that characteristically follows an indolent course. It is believed that infection or chronic inflammation may be triggers for malignant transformation in the prostate, but it is of unknown etiology. Reports of MALT lymphomas of the prostate with other concurrent primary prostate cancers are even more limited. We present the unique case of a 67-year-old male with concurrent adenocarcinoma of the prostate and primary MALT lymphoma of the prostate. The patient was treated with standard therapy for prostate adenocarcinoma, which would also treat a primary MALT lymphoma. He has been disease-free for over one year for both his primary malignancies. This case confirms that MALT lymphoma can arise concurrently with adenocarcinoma of the prostate.

摘要

前列腺原发性黏膜相关淋巴组织(MALT)淋巴瘤是一种罕见疾病,其典型特征是病程进展缓慢。据信,感染或慢性炎症可能是前列腺恶性转化的触发因素,但其病因尚不清楚。关于前列腺MALT淋巴瘤合并其他原发性前列腺癌的报道更为有限。我们报告了一例独特病例,一名67岁男性同时患有前列腺腺癌和原发性前列腺MALT淋巴瘤。该患者接受了前列腺腺癌的标准治疗,这种治疗方法也可用于治疗原发性MALT淋巴瘤。他的两种原发性恶性肿瘤均已无病生存超过一年。该病例证实,MALT淋巴瘤可与前列腺腺癌同时发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f6c/2994529/8784a8b0d795/rt-2010-3-e54-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f6c/2994529/f9fc281d154f/rt-2010-3-e54-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f6c/2994529/bf45401e684d/rt-2010-3-e54-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f6c/2994529/1fec154096c0/rt-2010-3-e54-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f6c/2994529/8784a8b0d795/rt-2010-3-e54-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f6c/2994529/f9fc281d154f/rt-2010-3-e54-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f6c/2994529/bf45401e684d/rt-2010-3-e54-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f6c/2994529/1fec154096c0/rt-2010-3-e54-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f6c/2994529/8784a8b0d795/rt-2010-3-e54-g004.jpg

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本文引用的文献

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Is there a role for Helicobacter pylori infection in urological diseases?幽门螺杆菌感染在泌尿系统疾病中起作用吗?
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Primary mucosa-associated lymphoid tissue lymphoma of the prostate: tumor relapse 7 years after local therapy.前列腺原发性黏膜相关淋巴组织淋巴瘤:局部治疗7年后肿瘤复发。
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The prostate-associated lymphoid tissue (PALT) is linked to the expression of homing chemokines CXCL13 and CCL21.前列腺相关淋巴组织(PALT)与归巢趋化因子CXCL13和CCL21的表达相关。
Prostate. 2007 Jul 1;67(10):1070-80. doi: 10.1002/pros.20604.
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Am J Surg Pathol. 2005 May;29(5):693-9. doi: 10.1097/01.pas.0000153122.65138.b1.
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