Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72205, USA.
Ann Biomed Eng. 2011 Mar;39(3):964-72. doi: 10.1007/s10439-010-0231-z. Epub 2010 Dec 8.
Changes in fetal magnetocardiographic (fMCG) signals are indicators for fetal body movement. We propose a novel approach to reliably extract fetal body movements based on the field strength of the fMCG signal independent of its frequency. After attenuating the maternal MCG, we use a Hilbert transform approach to identify the R-wave. At each R-wave, we compute the center-of-gravity (cog) of the coordinate positions of MCG sensors, each weighted by the magnitude of the R-wave amplitude recorded at the corresponding sensor. We then define actogram as the distance between the cog computed at each R-wave and the average of the cog from all the R-waves in a 3-min duration. By applying a linear de-trending approach to the actogram we identify the fetal body movement and compare this with the synchronous occurrence of the acceleration in the fetal heart rate. Finally, we apply this approach to the fMCG recorded simultaneously with ultrasound from a single subject and show its improved performance over the QRS-amplitude based approach in the visually verified movements. This technique could be applied to transform the detection of fetal body movement into an objective measure of fetal health and enhance the predictive value of prevalent clinical testing for fetal wellbeing.
胎儿磁心图(fMCG)信号的变化是胎儿身体运动的指标。我们提出了一种新的方法,可以基于 fMCG 信号的场强可靠地提取胎儿的身体运动,而不依赖于其频率。在衰减母体 MCG 后,我们使用希尔伯特变换方法来识别 R 波。在每个 R 波处,我们计算 MCG 传感器坐标位置的重心(cog),每个位置的权重由相应传感器记录的 R 波幅度的大小决定。然后,我们将动作图定义为每个 R 波处计算的 cog 与 3 分钟内所有 R 波的 cog 平均值之间的距离。通过对动作图应用线性去趋势方法,我们识别出胎儿的身体运动,并将其与胎儿心率的加速度同时发生进行比较。最后,我们将该方法应用于从单个对象同时记录的 fMCG 和超声中,并展示其在视觉验证运动中优于基于 QRS 幅度的方法的性能。该技术可用于将胎儿身体运动的检测转化为胎儿健康的客观衡量标准,并提高现有临床测试对胎儿健康状况的预测价值。