Loginova S Ia, Borisevich S V, Shkliaeva O M, Maksimov V A, Bondarev V P, Nebol'sin V E
Antibiot Khimioter. 2010;55(7-8):10-2.
The experimental study of the Ingavirin efficacy against the influenza virus A (H5N1) on intranasally-infected albino mice vs. Tamiflue and Arbidol showed that when used for the prophylaxis, urgent prophylaxis and therapy it was effective in the protectiom of the animals from death. The efficient dose for the prophylaxis of the influenza infection was 5 mg/kg (protective efficacy of 46.7%) and for the urgent prophylaxis and therapy it was 15 mg/kg (protective efficacy of 40.0 and 35.0% respectively).
英加韦林对经鼻感染甲型流感病毒(H5N1)的白化小鼠的疗效与达菲和阿比多尔的对比实验研究表明,在用于预防、紧急预防和治疗时,它能有效保护动物免于死亡。预防流感感染的有效剂量为5毫克/千克(保护效力为46.7%),紧急预防和治疗的有效剂量为15毫克/千克(保护效力分别为40.0%和35.0%)。