Simpson Joanne K, Medina-Flores Rafael, Deng Jau-Shyong
Department of Dermatology, Veterans Administration Medical Center, University Dr C, Pittsburgh, PA 15240, USA.
Cutis. 2010 Oct;86(4):195-8.
We describe a 51-year-old white man with discoid lupus erythematosus (DLE) of the head, neck, trunk, and upper extremities of more than 20 years' duration who developed rapidly progressive squamous cell carcinoma (SCC) of the bilateral ear helices. Human papillomavirus (HPV) was detected from excised specimens from the ears via tissue immunohistochemistry. Human papillomavirus infection of discoid lesions may be responsible for the rapid progression of SCC of this patient's bilateral ear helices.
我们描述了一名51岁的白人男性，患有头、颈、躯干和上肢的盘状红斑狼疮（DLE）超过20年，其双侧耳轮迅速发展为进展性鳞状细胞癌（SCC）。通过组织免疫组化从耳部切除标本中检测到人乳头瘤病毒（HPV）。盘状病变的人乳头瘤病毒感染可能是该患者双侧耳轮鳞状细胞癌快速进展的原因。
