Adelman H M, Wallach P M, Gutierrez F, Kreitzer S M, Seleznick M J, Espinoza C G, Espinoza L R
Department of Internal Medicine, University of South Florida Health Sciences Center, Tampa.
Cutis. 1994 Aug;54(2):111-4.
Various conditions can imitate cutaneous vasculitis. Scurvy is a less appreciated cause of rash that can resemble vasculitis. Three patients were referred to our rheumatology service for "vasculitis," who subsequently were found to have scurvy. Findings included a purpuric skin rash, myalgias, and malaise. The patients had low vitamin C levels and findings on skin biopsy specimens indicative of scurvy. The three patients were on idiosyncratic diets deficient in vitamin C, and the two patients who allowed us to administer vitamin C therapy improved clinically. We emphasize the importance of a careful dietary history. Early recognition of scurvy is important because it can be treated specifically, and toxic treatment of vasculitis can be avoided.
多种情况可模仿皮肤血管炎。坏血病是一种较少被认识到的可类似血管炎的皮疹病因。三名因“血管炎”转诊至我们风湿科的患者，后来被发现患有坏血病。表现包括紫癜性皮疹、肌痛和不适。这些患者维生素C水平低，皮肤活检标本有提示坏血病的表现。这三名患者饮食特殊，缺乏维生素C，而两名允许我们给予维生素C治疗的患者临床症状有所改善。我们强调仔细询问饮食史的重要性。早期识别坏血病很重要，因为它可以得到特异性治疗，且可避免对血管炎进行不当治疗。
