Aalborg County Hospital, Aalborg SV, Denmark.
APMIS. 2011 Jan;119(1):44-8. doi: 10.1111/j.1600-0463.2010.02690.x. Epub 2010 Oct 25.
The objective of this study was to evaluate the association between changes revealed by computerized tomography scan (CT) and symptoms, signs, and bacteriological diagnoses in a general practice population who had been diagnosed with acute maxillary sinusitis (AMS). This study was designed as a prospective cohort study in Danish general practice in cooperation with the otorhinolaryngology and neuroradiology departments at Aalborg County Hospital. One hundred and seventy-four patients, aged 18-65 years, suspected of having AMS were included. The strongest associations were with purulent nasal discharge, preceding upper respiratory tract infection, maxillary toothache and oedema over the maxillary sinuses. Self-reported previous sinusitis was negatively associated with sinus infection. There was a strong association between increasing values of C-reactive protein (CRP) and erythrocyte sedimentation rate and changes on the CT scan. CT scans contributed only little to the final diagnosis, whereas increased CRP values and elevated erythrocyte sedimentation rates were more reliable indicators of inflammation in the sinuses.
本研究旨在评估计算机断层扫描 (CT) 显示的变化与普通人群中急性上颌窦炎 (AMS) 患者的症状、体征和细菌学诊断之间的关系。该研究是在丹麦普通实践中与奥尔堡县医院耳鼻喉科和神经放射科合作进行的前瞻性队列研究。纳入了 174 名年龄在 18-65 岁之间、疑似患有 AMS 的患者。与脓性鼻涕、上呼吸道感染、上颌牙痛和上颌窦肿胀最相关。自我报告的既往鼻窦炎与鼻窦感染呈负相关。C 反应蛋白 (CRP) 值和红细胞沉降率升高与 CT 扫描上的变化之间存在很强的关联。CT 扫描对最终诊断的贡献不大,而 CRP 值升高和红细胞沉降率升高是鼻窦炎症更可靠的指标。