Veríssimo Carlos, Matos Teresa, Dutschman Luís, Rocha Isilda
Serviço de Ginecologia/Obstetrícia, Hospital Fernando Fonseca, Amadora.
Acta Med Port. 2010 Sep-Oct;23(5):921-6. Epub 2010 Oct 22.
Antiphospholipid Syndrome (APS) is an immune thrombophylia of unknown etiology which leads to vascular thrombosis and gestational complications.
A 27-year old woman who had been diagnosed APS four years before was admitted in the Emergency Room five days after a spontaneous delivery due to [corrected] pain in the upper right abdominal quadrant. Blood analysis revealed AST and ALT rise and thrombocytopenia. CT scan was suggestive of liver infarction due to venous ischemia. Abdominal eco-doppler diagnosed vena porta left branch thrombosis and compensatory arterial circulation. Treatment included low molecular weight heparin and corticosteroids which led to progressive clinical, laboratory and imagiological recovery.
Portal venous system thrombosis is extremely rare in the absence of local risk factors and the most common and catastrophic complication is intestinal necrosis.
抗磷脂综合征（APS）是一种病因不明的免疫性血栓形成倾向疾病，可导致血管血栓形成和妊娠并发症。
一名27岁女性，四年前被诊断为APS，在自然分娩五天后因右上腹疼痛入住急诊室。血液分析显示谷草转氨酶（AST）和谷丙转氨酶（ALT）升高以及血小板减少。计算机断层扫描（CT）提示因静脉缺血导致肝梗死。腹部超声多普勒诊断为门静脉左支血栓形成及代偿性动脉循环。治疗包括低分子量肝素和皮质类固醇，随后患者在临床、实验室检查及影像学方面逐渐恢复。
在没有局部危险因素的情况下，门静脉系统血栓形成极为罕见，最常见且灾难性的并发症是肠坏死。
