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2008 年英国社区腹泻病例隐孢子虫检测和报告的临床实验室实践。

Clinical laboratory practices for detection and reporting of Cryptosporidium in community cases of diarrhoea in the United Kingdom, 2008.

机构信息

Cryptosporidium Reference Unit, Public Health Wales Microbiology, Singleton Hospital, Swansea, Wales, United Kingdom.

出版信息

Euro Surveill. 2010 Dec 2;15(48):19731. doi: 10.2807/ese.15.48.19731-en.

Abstract

To identify procedures employed by publicly funded clinical diagnostic laboratories in the United Kingdom (UK) for the detection of Cryptosporidium in community cases of diarrhoea, a telephone survey was conducted between August 2008 and January 2009 of all such laboratories that test stools from community-based patients. All 200 laboratories responded: 145 (72.5%) tested all stool samples for Cryptosporidium, while 55 (27.5%) applied selection criteria. There were country and regional differences in the proportion of laboratories selectively testing stools, which were significantly correlated with Cryptosporidium report rates to national surveillance (Spearman's rank correlation coefficient (rs)=0.61, degrees of freedom (df)=11, p=0.03). Understanding of laboratory practice is fundamental to interpreting trends in surveillance data, estimating disease burden and identifying outbreaks, as well as providing important background information against which changes and effects of new public health regulations can be measured.

摘要

为了确定英国(UK)公共资助临床诊断实验室在社区腹泻病例中检测隐孢子虫的方法,我们于 2008 年 8 月至 2009 年 1 月间对所有检测社区患者粪便的此类实验室进行了电话调查。所有 200 家实验室均做出回应:145 家(72.5%)实验室检测所有粪便样本是否存在隐孢子虫,55 家(27.5%)实验室采用了选择标准。各实验室选择性检测粪便的比例存在国家和地区差异,与国家监测报告的隐孢子虫报告率呈显著相关(Spearman 等级相关系数(rs)=0.61,自由度(df)=11,p=0.03)。了解实验室实践情况对于解释监测数据趋势、评估疾病负担和识别疫情以及提供重要背景信息至关重要,这些信息可用来衡量新公共卫生法规的变化及其影响。

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